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MDM2 Proteins

(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues. [provided by RefSeq, Jul 2008].
MDM2 Protein (AA 1-491) (GST tag) MDM2 Protein (AA 1-491) (GST tag) MDM2 Protein (AA 1-491) (GST tag) (ABIN1310600)

MDM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

MDM2 Protein (AA 1-118) (His tag) MDM2 Protein (AA 1-118) (His tag) MDM2 Protein (AA 1-118) (His tag) (ABIN7123867)

MDM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

MDM2 Protein (AA 1-300) (His tag) MDM2 Protein (AA 1-300) (His tag) MDM2 Protein (AA 1-300) (His tag) (ABIN7123866)

MDM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

MDM2 Proteins by Origin

Find MDM2 Proteins for a variety of species such as anti-Human MDM2, anti-Mouse MDM2, anti-Cat MDM2. The species listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Proteins by Source

Here you will find MDM2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MDM2 Proteins by Protein Type

Here you can find MDM2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

MDM2 Proteins by Application

Find MDM2 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MDM2 Proteins by Biological Activity

Find MDM2 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular MDM2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1310600
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123867
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123866
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310602
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408738
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408735
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093782
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3133375
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Yeast
Validations
  • (1)
Cat. No. ABIN5713638
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709925
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6239916
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6700260
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6700258
Quantity 50 μg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Source Yeast
Validations
Cat. No. ABIN1656044
Quantity 1 mg
Datasheet Datasheet
Reactivity Xenopus laevis
Source Yeast
Validations
Cat. No. ABIN1477646
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MDM2 Proteins

Zhang, Zhong, Chen: "LC-MS/MS-based targeted proteomics quantitatively detects the interaction between p53 and MDM2 in breast cancer." in: Journal of proteomics, Vol. 152, pp. 172-180, (2016) (PubMed).

Aliases for MDM2 Proteins

MDM2 proto-oncogene (MDM2) Proteins
MDM2 proto-oncogene S homeolog (mdm2.S) Proteins
MDM2 proto-oncogene (Mdm2) Proteins
Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) (MDM2) Proteins
MDM2 oncogene, E3 ubiquitin protein ligase (mdm2) Proteins
transformed mouse 3T3 cell double minute 2 (Mdm2) Proteins
1700007J15Rik Proteins
AA415488 Proteins
ACTFS Proteins
hdm2 Proteins
HDMX Proteins
Mdm-2 Proteins
zgc:109834 Proteins
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