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Sialic Acid Binding Ig-Like Lectin 15 Proteins (SIGLEC15)

Binds sialylated glycoproteins.. Additionally we are shipping SIGLEC15 Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SIGLEC15 SIGLEC15 498888  
SIGLEC15 284266 Q6ZMC9
Mouse SIGLEC15 SIGLEC15 620235  
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Top SIGLEC15 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

SIGLEC15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) Interaction Partners

Human Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) interaction partners

  1. Siglec-15 recognizes the tumoral sTn (show EEF1A2 Proteins) antigen and transduces a signal for enhanced TGF-beta (show TGFB1 Proteins) secretion in TAMs

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) interaction partners

  1. Siglec-15 does not mediate joint destruction in inflammatory arthritis

  2. The present findings indicate that Siglec-15 is involved in estrogen deficiency-induced differentiation of osteoclasts and is thus a potential therapeutic target for postmenopausal osteoporosis.

  3. Siglec-15 regulates osteoclast development and bone resorption by modulating receptor activator of nuclear factor kappaB ligand (RANKL (show TNFSF11 Proteins)) signaling in association with DAP12 (show TYROBP Proteins).

  4. DC-STAMP, Siglec-15, Tspan7 (show TSPAN7 Proteins) and Mst1r (show MST1R Proteins) expression was downregulated by docosahexaenoic acid, but not eicosapentaenoic acid during osteoclastogenesis in vitro.

  5. results reveal the importance of Siglec-15 in the regulation of osteoclast formation and/or function in vivo, providing new insights into osteoclast biology

  6. the Siglec-15-DAP12 (show TYROBP Proteins)-Syk (show SYK Proteins)-signaling cascade plays a critical role in functional osteoclast formation.

  7. These results suggest that Siglec-15 plays an important role in osteoclast differentiation.

SIGLEC15 Protein Profile

Protein Summary

Binds sialylated glycoproteins.

Gene names and symbols associated with SIGLEC15

  • sialic acid binding Ig-like lectin 15 (Siglec15)
  • sialic acid binding Ig-like lectin 15 (SIGLEC15)
  • Cd33l3 protein
  • EG620235 protein
  • HsT1361 protein
  • RGD1565948 protein
  • SIGLEC-15 protein
  • SIGLEC-I protein

Protein level used designations for SIGLEC15

sialic acid-binding Ig-like lectin 15 , CD33 antigen-like 3 , CD33 molecule-like 3

GENE ID SPECIES
498888 Rattus norvegicus
284266 Homo sapiens
620235 Mus musculus
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