Browse our anti-Integrin beta 2 (ITGB2) Antibodies

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anti-Integrin beta 2 Antibodies (ITGB2)
On www.antibodies-online.com are 676 Integrin beta 2 (ITGB2) Antibodies from 30 different suppliers available. Additionally we are shipping Integrin beta 2 Proteins (16) and Integrin beta 2 Kits (12) and many more products for this protein. A total of 711 Integrin beta 2 products are currently listed.
Synonyms:
2E6, AI256028, AI528527, CD18, D12S370, ITGB2, LAD, LCAMB, LFA-1, Lfa1, LT-BETA-R, Ltar, LTbetaR, MAC-1, MF17, MFI7, TNF-R-III, Tnfbr, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRrp, TNFRSF3
list all antibodies Gene Name GeneID UniProt
ITGB2 16414 P11835
ITGB2 309684  
ITGB2 3689 P05107

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Top referenced anti-Integrin beta 2 Antibodies

  1. Human Monoclonal Integrin beta 2 Primary Antibody for Func, FACS - ABIN111902 : Drbal, Angelisová, Cerný, Hilgert, Horejsí: A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins. in Immunobiology 2001 (PubMed)
    Show all 9 references for 111902

  2. Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody for FACS, IHC (fro) - ABIN118151 : Trowbridge, Omary: Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. in The Journal of experimental medicine 1982 (PubMed)
    Show all 5 references for 118151

  3. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody for FACS - ABIN118555 : Bindon, Hale, Waldmann: Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies. in European journal of immunology 1988 (PubMed)
    Show all 3 references for 118555

  4. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody for FACS - ABIN118552 : Chabanne, Marchal, Kaplanski, Fournel, Magnol, Monier, Rigal: Screening of 78 monoclonal antibodies directed against human leukocyte antigens for cross-reactivity with surface markers on canine lymphocytes. in Tissue antigens 1994 (PubMed)
    Show all 3 references for 118552

  5. Rat (Rattus) Monoclonal Integrin beta 2 Primary Antibody for FACS, IHC (fro) - ABIN120418 : Tamatani, Kotani, Miyasaka: Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. in European journal of immunology 1991 (PubMed)
    Show all 2 references for 120418

  6. Human Polyclonal Integrin beta 2 Primary Antibody for IF, ELISA - ABIN1532556 : Kishimoto, OConnor, Lee, Roberts, Springer: Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. in Cell 1987 (PubMed)
    Show all 2 references for 1532556

  7. Human Polyclonal Integrin beta 2 Primary Antibody for IF, ELISA - ABIN1531540 : Hattori, Fujiyama, Taylor, Watanabe, Yada, Park, Toyoda, Ishii, Totoki, Choi, Groner, Soeda, Ohki, Takagi, Sakaki, Taudien, Blechschmidt, Polley, Menzel, Delabar, Kumpf, Lehmann, Patterson, Reichwald et al.: The DNA sequence of human chromosome 21. ... in Nature 2000 (PubMed)
    Show all 2 references for 1531540

  8. Human Monoclonal Integrin beta 2 Primary Antibody for FACS - ABIN111901 : Drbal, Angelisová, Hilgert, Cerný, Novák, Horejsí: A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells. in Blood 2001 (PubMed)

More Antibodies against Integrin beta 2 Interaction Partners

Mouse (Murine) Integrin beta 2 (ITGB2) interaction partners

  1. lymphatic vessel expansion occurs in two distinct phases; the first wave of expansion is dependent on IL-7 (show IL7 Antibodies); the second phase, responsible for leukocyte exit from the glands, is regulated by lymphotoxin (show LTB Antibodies) (LT)betaR signaling

  2. both GDF-15 (show GDF15 Antibodies) and TGF-beta1 (show TGFB1 Antibodies) counteract chemokine (show CCL1 Antibodies)-induced integrin activation on neutrophils via the ALK-5 (show TGFBR1 Antibodies)/TGF-betaRII heterodimer.

  3. the Slam (show SLAMF1 Antibodies) locus has an overall inhibitory role during NK cell activation that is solely dependent on 2B4 (show CD244 Antibodies). This effect is influenced by cytokines and leads to suppression of LFA-1 (show ITGAL Antibodies) activity.

  4. Wild-type C57BL/6 mice with pristane-induced lupus developed a strong IFN signature, which was absent in immunoglobulin-deficient (muMT), C3(-/-) , and CD18(-/-) mice.

  5. Study suggest an important impact of NKT (show CTSL1 Antibodies) cells and postulate a critical function for LFA-1 (show ITGAL Antibodies) during processes of liver regeneration.

  6. NDR1 (show STK38 Antibodies) kinase, activated by the Rap1 (show TERF2IP Antibodies) signaling cascade through RAPL (show RASSF5 Antibodies) and Mst1 (show MST1 Antibodies)/Mst2 (show STK3 Antibodies), associated with and recruited kindlin-3 (show FERMT3 Antibodies) to the immunological synapses, which was required for high-affinity LFA-1 (show ITGAL Antibodies)/ICAM-1 (show ICAM1 Antibodies) binding.

  7. LTbetaR is essential for efficient liver regeneration and cooperates with TNFRp55 (show TNFRSF1A Antibodies) in this process. Differences in survival kinetics strongly suggest distinct functions for these two cytokine receptors in liver regeneration.

  8. SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.

  9. Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 (show ITGAL Antibodies) activation and neutrophil arrest in vivo

  10. report that beta2 and alpha4 integrins use different RIAM (show APBB1IP Antibodies)-dependent and -independent pathways to undergo activation by talin

Human Integrin beta 2 (ITGB2) interaction partners

  1. The single nucleotide polymorphism rs1143678 substitutes Pro(1146) for Ser (show SIGLEC1 Antibodies) in the integrin alphaM cytoplasmic tail generates a noncanonical 14-3-3zeta (show YWHAZ Antibodies) binding site that modulates integrin alphaM(PS)beta2 outside-in signaling

  2. this study shows that cross-talk between LFA-1 (show ITGAL Antibodies) and Notch1 (show NOTCH1 Antibodies) through the Akt (show AKT1 Antibodies)/ERK (show EPHB2 Antibodies)-GSK3beta (show GSK3b Antibodies) signaling enhances T cell differentiation toward Th1 (show TH1L Antibodies)

  3. FRbeta (show FOLR2 Antibodies) as a novel CD11b/CD18 (show ITGAM Antibodies) regulator for trafficking and homing of a subset of macrophages on collagen.

  4. The results show that with LFA-1 (show ITGAL Antibodies) antibodies, we can activate LFA-1 (show ITGAL Antibodies) and inhibit alpha4beta1, inhibit both LFA-1 (show ITGAL Antibodies) and alpha4beta1, inhibit LFA-1 (show ITGAL Antibodies) but not alpha4beta1, or not affect LFA-1 (show ITGAL Antibodies) or alpha4beta1

  5. K152 and D120 within the PH domain of SKAP55 (show SKAP1 Antibodies) regulate plasma membrane targeting and T cell receptor-mediated activation of LFA-1 (show ITGAL Antibodies).

  6. LIGHT and LTBR (show LTBR Antibodies) interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.

  7. Genetic inactivation and blockade studies revealed that homophilic interactions between intercellular adhesion molecule 1 (ICAM-1 (show ICAM1 Antibodies)) expressed on tumor cells and MSCs, respectively, regulate the competition between tumor cells and HSPCs for binding to MSCs. Moreover, tumor cell-secreted soluble ICAM-1 (show ICAM1 Antibodies)(sICAM-1) also impaired HSPC (show PSMA7 Antibodies) adhesion via blocking CD18-ICAM-1 (show ICAM1 Antibodies) binding between HSPCs and MSCs

  8. The ability of simvastatin to target CR3 (show ITGAM Antibodies) in its ligand binding-activated conformation is a novel mechanism to explain the known anti-inflammatory effects of this compound, in particular because this CR3 (show ITGAM Antibodies) conformation is found in pro-inflammatory environments.

  9. CD18 methylation and age greater than 65 years were independent prognostic factors of thrombosis complicated by primary myelofibrosis.

  10. We found that LTbetaR polymorphisms caused severe BPH (show GLI3 Antibodies). Thus, LTbetaR may contribute to the risk of BPH (show GLI3 Antibodies) development.

Cow (Bovine) Integrin beta 2 (ITGB2) interaction partners

  1. Identification of numerous variations in exonic and intronic regions within the ITGB2 gene in Bos taurus and indicus screened for bovine leukocyte adhesion deficiency.

  2. intramammarily administered lipopolysaccharides seem to play an important role in modulating L-selectin (show SELL Antibodies) and beta2 integrin expression on circulating bovine polymorphonuclear leukocytes

  3. A delay in apoptosis was demonstrated in CD18-deficient bovine neutrophils and this appeared to be closely associated with lowered signalling via [Ca2 (show CA2 Antibodies)+]i, diminished annexin V (show ANXA5 Antibodies) expression on the cell surface, and decreased caspase 3 (show CASP3 Antibodies) activity in lysates

  4. The I-EGF (show EGF Antibodies)-3 domain of bovine CD18 (amino acid residues 541-581) is critical for conferring species-specific susceptibility to Mannheimia haemolytica leukotoxin.

  5. These results clearly indicate that the bovine CD18 subunit of beta(2)-integrins is the functional receptor for M. haemolytica Lkt.[ruminant-specific leukotoxin]

  6. study provides evidence that the expression of CD18 was downregulated by the plasma glycoforms of alpha-1 acid glycoprotein (show ORM1 Antibodies) and inhibited the chemotaxis of monocytes

  7. Loss of CD18 is associated with bovine leukocyte adhesion deficiency.

  8. Intact signal peptide of CD18, the beta-subunit (show POLG Antibodies) of beta2-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin.

Pig (Porcine) Integrin beta 2 (ITGB2) interaction partners

  1. CR3 (show ITGAM Antibodies) plays a cardinal (show CARD8 Antibodies) role in beta-glucan signalling in porcine neutrophils, while macrophages use a more diverse receptor array to detect and respond towards beta-glucans.

  2. The expression of zona pellucida glycoprotein 3 (show ZP3 Antibodies) and integrin beta-2 in oocytes after brilliant cresyl blue staining is reported.

  3. early CD18 downregulation is profitable for the host in a situation with an intense LPS (show IRF6 Antibodies) stimulus

  4. It is concluded that porcine CD18 is necessary to mediate A. pleuropneumoniae ApxIIIA toxin-induced leukolysis.

Goat Integrin beta 2 (ITGB2) interaction partners

  1. Integrin CD11c (show ITGAX Antibodies)/CD18 alpha-chain (show FCGRT Antibodies) phosphorylation is functionally important.

Integrin beta 2 (ITGB2) Antigen Profile

Antigen Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Alternative names and synonyms associated with Integrin beta 2 (ITGB2)

  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2) antibody
  • integrin, beta 2 (ITGB2) antibody
  • integrin beta 2 (Itgb2) antibody
  • integrin, beta 2 (Itgb2) antibody
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (CD18) antibody
  • lymphotoxin B receptor (Ltbr) antibody
  • lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR) antibody
  • 2E6 antibody
  • AI256028 antibody
  • AI528527 antibody
  • CD18 antibody
  • D12S370 antibody
  • ITGB2 antibody
  • LAD antibody
  • LCAMB antibody
  • LFA-1 antibody
  • Lfa1 antibody
  • LT-BETA-R antibody
  • Ltar antibody
  • LTbetaR antibody
  • MAC-1 antibody
  • MF17 antibody
  • MFI7 antibody
  • TNF-R-III antibody
  • Tnfbr antibody
  • TNFCR antibody
  • TNFR-RP antibody
  • TNFR2-RP antibody
  • TNFR3 antibody
  • TNFRrp antibody
  • TNFRSF3 antibody

Protein level used designations for anti-Integrin beta 2 (ITGB2) Antibodies

integrin beta-2 , Mac-1 beta , cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , complement receptor C3 subunit beta , lymphocyte function associated antigen 1 , macrophage antigen-1 beta , CD18 leukocyte adhesion molecule , integrin beta 2 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) , macrophage antigen 1 (mac-1) beta subunit) , cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor) , complement receptor C3 beta-subunit , integrin beta chain, beta 2 , leukocyte cell adhesion molecule CD18 , leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C , CD18 subunit , Leu-CAM receptor , integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2) , integrin beta 2 subunit , Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , Complement receptor C3 subunit beta , Integrin beta-2 , antigen CD18 , integrin beta-2 chain , LT beta-R , LT-beta receptor , TNF receptor-related protein , lymphotoxin-beta receptor , tumor necrosis factor receptor superfamily member 3 , tumor necrosis factor receptor superfamily, member 3 , lymphotoxin B receptor , tumor necrosis factor C receptor , tumor necrosis factor receptor 2-related protein , tumor necrosis factor receptor type III

GENE ID SPECIES
458607 Pan troglodytes
710577 Macaca mulatta
16414 Mus musculus
309684 Rattus norvegicus
3689 Homo sapiens
281877 Bos taurus
396943 Sus scrofa
396181 Gallus gallus
100861185 Capra hircus
494433 Ovis aries
17000 Mus musculus
4055 Homo sapiens
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