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Browse our anti-Integrin beta 2 (ITGB2) Antibodies

Full name:
anti-Integrin beta 2 Antibodies (ITGB2)
On www.antibodies-online.com are 608 Integrin beta 2 (ITGB2) Antibodies from 28 different suppliers available. Additionally we are shipping Integrin beta 2 Kits (16) and Integrin beta 2 Proteins (16) and many more products for this protein. A total of 647 Integrin beta 2 products are currently listed.
Synonyms:
2E6, AI256028, AI528527, CD18, D12S370, ITGB2, LAD, LCAMB, LFA-1, Lfa1, LT-BETA-R, Ltar, LTbetaR, MAC-1, MF17, MFI7, TNF-R-III, Tnfbr, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRrp, TNFRSF3
list all antibodies Gene Name GeneID UniProt
ITGB2 16414 P11835
ITGB2 309684  
ITGB2 3689 P05107

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All available anti-Integrin beta 2 Antibodies

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Top referenced anti-Integrin beta 2 Antibodies

  1. Human Monoclonal Integrin beta 2 Primary Antibody for Func, FACS - ABIN111902 : Drbal, Angelisová, Cerný, Hilgert, Horejsí: A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins. in Immunobiology 2001 (PubMed)
    Show all 9 references for ABIN111902

  2. Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody for FACS, IHC (fro) - ABIN118151 : Trowbridge, Omary: Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. in The Journal of experimental medicine 1982 (PubMed)
    Show all 5 references for ABIN118151

  3. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody for FACS - ABIN118555 : Bindon, Hale, Waldmann: Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies. in European journal of immunology 1988 (PubMed)
    Show all 3 references for ABIN118555

  4. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody for FACS - ABIN118552 : Chabanne, Marchal, Kaplanski, Fournel, Magnol, Monier, Rigal: Screening of 78 monoclonal antibodies directed against human leukocyte antigens for cross-reactivity with surface markers on canine lymphocytes. in Tissue antigens 1994 (PubMed)
    Show all 3 references for ABIN118552

  5. Rat (Rattus) Monoclonal Integrin beta 2 Primary Antibody for FACS, IHC (fro) - ABIN120418 : Tamatani, Kotani, Miyasaka: Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. in European journal of immunology 1991 (PubMed)
    Show all 2 references for ABIN120418

  6. Human Polyclonal Integrin beta 2 Primary Antibody for IF, ELISA - ABIN1532556 : Kishimoto, OConnor, Lee, Roberts, Springer: Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. in Cell 1987 (PubMed)
    Show all 2 references for ABIN1532556

  7. Human Polyclonal Integrin beta 2 Primary Antibody for IF, ELISA - ABIN1531540 : Hattori, Fujiyama, Taylor, Watanabe, Yada, Park, Toyoda, Ishii, Totoki, Choi, Groner, Soeda, Ohki, Takagi, Sakaki, Taudien, Blechschmidt, Polley, Menzel, Delabar, Kumpf, Lehmann, Patterson, Reichwald et al.: The DNA sequence of human chromosome 21. ... in Nature 2000 (PubMed)
    Show all 2 references for ABIN1531540

  8. Human Monoclonal Integrin beta 2 Primary Antibody for FACS - ABIN111901 : Drbal, Angelisová, Hilgert, Cerný, Novák, Horejsí: A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells. in Blood 2001 (PubMed)

More Antibodies against Integrin beta 2 Interaction Partners

Mouse (Murine) Integrin beta 2 (ITGB2) interaction partners

  1. SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.

  2. Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 (show ITGAL Antibodies) activation and neutrophil arrest in vivo

  3. report that beta2 and alpha4 integrins use different RIAM (show APBB1IP Antibodies)-dependent and -independent pathways to undergo activation by talin

  4. Timely blockade of ICAM-1 (show ICAM1 Antibodies).LFA-1 (show ITGAL Antibodies) interaction prevents disease onset in a mouse model of emphysema.

  5. This study identified Mrp8 (show S100A8 Antibodies)/14 and TLR4 (show TLR4 Antibodies) as important modulators of the leukocyte recruitment cascade during inflammation via integrin beta2.

  6. Anti-OX40L (show TNFSF4 Antibodies) mAb could prolong secondary heart allograft survival based on CD40 (show CD40 Antibodies)/CD40L (show CD40LG Antibodies) and LFA-1 (show ITGAL Antibodies)/ICAM-1 (show ICAM1 Antibodies) blockade.

  7. Alzheimer's disease model mice lacking LFA-1 (show ITGAL Antibodies) were protected from cognitive decline

  8. Loss of the interaction between beta2-integrins and kindlin-3 (show FERMT3 Antibodies) abolishes the actin-linkage of integrins and the GM-CSF (show CSF2 Antibodies) receptor in dendritic cells.

  9. Optimal T cell activation and B cell antibody responses in vivo require the interaction between Integrin beta2 and kindlin-3 (show FERMT3 Antibodies).

  10. DC-derived LTBR (show LTBR Antibodies) ligands are critical mediators of lymph node cells survival, and LTBR (show LTBR Antibodies) signaling on reticular stromal cells is mediated by Pdpn (show PDPN Antibodies) expression.

Human Integrin beta 2 (ITGB2) interaction partners

  1. Critical role of the Mac1 (show ITGAM Antibodies)/NOX2 (show CYBB Antibodies) pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration

  2. Contact-activated C3(H2O) is a novel ligand for CD11b/CD18 (show ITGAM Antibodies) that mediates platelet-PMN (show TBCE Antibodies) complex formation and the binding of platelet-derived microparticles to PMNs.

  3. The expression level of Mac-1 (show ITGAM Antibodies) correlated with the number of neutrophils in patients with serous, endometrioid and undifferentiated epithelial ovarian cancer.

  4. Data show that secreted aspartic protease 2 (Sap2) of Candida albicans inactivates human macrophage complement factor H (factor H (show CFH Antibodies)), factor H (show CFH Antibodies)-receptors CD11b/CD18 (show ITGAM Antibodies) and CD11c (show ITGAX Antibodies)/CD18.

  5. Rerefined beta2 integrin structures show pyroglutamic acid at the beta2 N terminus and bending within the EGF1 (show GFM1 Antibodies) domain. Allostery is relayed to the alphaI domain by an internal ligand binding to a pocket at the interface between the beta-propeller and betaI domains.

  6. Four new mutations in the ITGB2 gene were found. These results can be used for decisive genetic diagnosis, genetic counseling, as well as prenatal diagnosis for all patients who are suspended to Leukocyte adhesion deficiency type I (LAD (show DLD Antibodies)-I).

  7. Contact-dependent lung adenocarcinoma aggregate dispersion by M2a macrophages occurs via ICAM-1 (show ICAM1 Antibodies) and beta2 integrin interactions.

  8. specific LFA-1 (show ITGAL Antibodies) binding partners that may play a role in regulating LFA-1 (show ITGAL Antibodies) activity in dendritic cells.

  9. The blood levels of CD18 soluble form were decreased in chronic rheumatoid arthritis patients.

  10. Data show that residues Ser745 and Ser756 in the integrin beta2 tail, which are adjacent to the NxxF motif, are required for docking protein 1 (show DOK1 Antibodies), docking protein 1 (show DOK1 Antibodies), 62kDa (show GTF2H1 Antibodies) (downstream of tyrosine kinase 1) (Dok1 (show DOK1 Antibodies)) interaction.

Cow (Bovine) Integrin beta 2 (ITGB2) interaction partners

  1. Identification of numerous variations in exonic and intronic regions within the ITGB2 gene in Bos taurus and indicus screened for bovine leukocyte adhesion deficiency.

  2. intramammarily administered lipopolysaccharides seem to play an important role in modulating L-selectin (show SELL Antibodies) and beta2 integrin expression on circulating bovine polymorphonuclear leukocytes

  3. A delay in apoptosis was demonstrated in CD18-deficient bovine neutrophils and this appeared to be closely associated with lowered signalling via [Ca2 (show CA2 Antibodies)+]i, diminished annexin V (show ANXA5 Antibodies) expression on the cell surface, and decreased caspase 3 (show CASP3 Antibodies) activity in lysates

  4. The I-EGF (show EGF Antibodies)-3 domain of bovine CD18 (amino acid residues 541-581) is critical for conferring species-specific susceptibility to Mannheimia haemolytica leukotoxin.

  5. These results clearly indicate that the bovine CD18 subunit of beta(2)-integrins is the functional receptor for M. haemolytica Lkt.[ruminant-specific leukotoxin]

  6. study provides evidence that the expression of CD18 was downregulated by the plasma glycoforms of alpha-1 acid glycoprotein (show ORM1 Antibodies) and inhibited the chemotaxis of monocytes

  7. Loss of CD18 is associated with bovine leukocyte adhesion deficiency.

  8. Intact signal peptide of CD18, the beta-subunit (show POLG Antibodies) of beta2-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin.

Pig (Porcine) Integrin beta 2 (ITGB2) interaction partners

  1. CR3 (show ITGAM Antibodies) plays a cardinal (show CARD8 Antibodies) role in beta-glucan signalling in porcine neutrophils, while macrophages use a more diverse receptor array to detect and respond towards beta-glucans.

  2. The expression of zona pellucida glycoprotein 3 (show ZP3 Antibodies) and integrin beta-2 in oocytes after brilliant cresyl blue staining is reported.

  3. early CD18 downregulation is profitable for the host in a situation with an intense LPS (show IRF6 Antibodies) stimulus

  4. It is concluded that porcine CD18 is necessary to mediate A. pleuropneumoniae ApxIIIA toxin-induced leukolysis.

Goat Integrin beta 2 (ITGB2) interaction partners

  1. Integrin CD11c (show ITGAX Antibodies)/CD18 alpha-chain (show FCGRT Antibodies) phosphorylation is functionally important.

Integrin beta 2 (ITGB2) Antigen Profile

Antigen Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Alternative names and synonyms associated with Integrin beta 2 (ITGB2)

  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2) antibody
  • integrin, beta 2 (ITGB2) antibody
  • integrin beta 2 (Itgb2) antibody
  • integrin, beta 2 (Itgb2) antibody
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (CD18) antibody
  • lymphotoxin B receptor (Ltbr) antibody
  • lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR) antibody
  • 2E6 antibody
  • AI256028 antibody
  • AI528527 antibody
  • CD18 antibody
  • D12S370 antibody
  • ITGB2 antibody
  • LAD antibody
  • LCAMB antibody
  • LFA-1 antibody
  • Lfa1 antibody
  • LT-BETA-R antibody
  • Ltar antibody
  • LTbetaR antibody
  • MAC-1 antibody
  • MF17 antibody
  • MFI7 antibody
  • TNF-R-III antibody
  • Tnfbr antibody
  • TNFCR antibody
  • TNFR-RP antibody
  • TNFR2-RP antibody
  • TNFR3 antibody
  • TNFRrp antibody
  • TNFRSF3 antibody

Protein level used designations for anti-Integrin beta 2 (ITGB2) Antibodies

integrin beta-2 , Mac-1 beta , cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , complement receptor C3 subunit beta , lymphocyte function associated antigen 1 , macrophage antigen-1 beta , CD18 leukocyte adhesion molecule , integrin beta 2 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) , macrophage antigen 1 (mac-1) beta subunit) , cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor) , complement receptor C3 beta-subunit , integrin beta chain, beta 2 , leukocyte cell adhesion molecule CD18 , leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C , CD18 subunit , Leu-CAM receptor , integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2) , integrin beta 2 subunit , Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , Complement receptor C3 subunit beta , Integrin beta-2 , antigen CD18 , integrin beta-2 chain , LT beta-R , LT-beta receptor , TNF receptor-related protein , lymphotoxin-beta receptor , tumor necrosis factor receptor superfamily member 3 , tumor necrosis factor receptor superfamily, member 3 , lymphotoxin B receptor , tumor necrosis factor C receptor , tumor necrosis factor receptor 2-related protein , tumor necrosis factor receptor type III

GENE ID SPECIES
458607 Pan troglodytes
710577 Macaca mulatta
16414 Mus musculus
309684 Rattus norvegicus
3689 Homo sapiens
281877 Bos taurus
396943 Sus scrofa
396181 Gallus gallus
100861185 Capra hircus
494433 Ovis aries
17000 Mus musculus
4055 Homo sapiens
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