anti-Mouse (Murine) Integrin beta 2 antibody for Enzyme Immunoassay

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • ITGB2
  • 2E6
  • AI528527
  • Cd18
  • LAD
  • LCAMB
  • Lfa1
  • MF17
  • CD18
  • LFA-1
  • MAC-1
  • MFI7
  • AI256028
  • LTbetaR
  • Ltar
  • TNF-R-III
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNFRrp
  • Tnfbr
  • Tnfrsf3
  • D12S370
  • LT-BETA-R
  • TNFR3
  • TNFRSF3
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
  • integrin, beta 2
  • integrin beta 2
  • lymphotoxin B receptor
  • lymphotoxin beta receptor (TNFR superfamily, member 3)
  • ITGB2
  • Itgb2
  • CD18
  • Ltbr
  • LTBR
Reactivity
Human, Mouse (Murine)
490
215
118
44
26
21
21
5
4
3
3
3
3
3
2
1
1
1
Host
Mouse
361
165
162
15
3
1
Clonality
Monoclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
88
74
53
20
15
12
9
8
8
7
7
7
6
6
6
6
5
5
5
5
4
3
3
3
3
3
3
3
3
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF)
488
291
203
147
95
90
75
68
52
40
28
18
11
9
7
7
6
2
1
1
1
1
1
1
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Catalog No. ABIN1105953
$ 390.50
Plus shipping costs $45.00

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Reactivity Human, Mouse (Murine)
(490), (215), (118), (44), (26), (21), (21), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1)
Host Mouse
(361), (165), (162), (15), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 2 antibody is un-conjugated
(88), (74), (53), (20), (15), (12), (9), (8), (8), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF)
(488), (291), (203), (147), (95), (90), (75), (68), (52), (40), (28), (18), (11), (9), (7), (7), (6), (2), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1105953) Images
Specificity Recognizes CD18 also known as ITGB2 (integrin beta chain beta 2).
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Ascites
Clone 1-00E-013
Isotype IgG2b

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1105953) Images back to top
Antigen
Alternative Name CD18 / ITGB2 (ITGB2 Antibody Abstract)
Background CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
Molecular Weight 85 kDa
Gene ID 3689
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling References for anti-Integrin beta 2 antibody (ABIN1105953) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details References for anti-Integrin beta 2 antibody (ABIN1105953) Images back to top
Format Liquid

References for anti-Integrin beta 2 antibody (ABIN1105953)

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling Images back to top
Background publications

Chakrabarti, Patel: "The atypical zeta (zeta) isoform of protein kinase C regulates CD11b/CD18 activation in human neutrophils." in: Microcirculation (New York, N.Y. : 1994), Vol. 15, Issue 6, pp. 555-67, 2008

Doisne, Castaigne, Deruyffelaere, Dieu-Nosjean, Chamot, Alcaide-Loridan, Charron, Al-Daccak: "The context of HLA-DR/CD18 complex in the plasma membrane governs HLA-DR-derived signals in activated monocytes." in: Molecular immunology, Vol. 45, Issue 3, pp. 709-18, 2007

Li, Tang, Puan, Law, Tan: "The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2." in: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24310-9, 2007

Images

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1105953) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Integrin beta 2 (ITGB2) antibody (ABIN1105953) anti-Integrin beta 2 (ITGB2) antibody
Immunofluorescence (IF) image for anti-Integrin beta 2 (ITGB2) antibody (ABIN1105953) anti-Integrin beta 2 (ITGB2) antibody (Image 2)