anti-Human TNFRSF13C antibody for Neutralization

Recommended TNFRSF13C Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies
  • RGD1560810
  • TNFRSF13C
  • BAFF-R
  • BAFFR
  • BROMIX
  • CD268
  • CVID4
  • prolixin
  • 2010006P15Rik
  • Baffr
  • Bcmd
  • Bcmd-1
  • Bcmd1
  • Lvis22
  • tumor necrosis factor receptor superfamily, member 13C
  • tumor necrosis factor receptor superfamily, member 13c
  • tumor necrosis factor receptor superfamily member 13C-like
  • TNFRSF13C
  • Tnfrsf13c
  • LOC618516
Epitope
AA 2-71
18
11
11
10
5
4
4
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
Reactivity
Human
147
104
41
5
2
2
2
2
1
Host
Goat
91
71
60
2
Clonality
Polyclonal
Conjugate
This TNFRSF13C antibody is un-conjugated
19
12
12
8
8
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
123
85
65
44
41
13
9
9
7
5
4
3
3
3
1
1
1
Supplier
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Catalog No. ABIN4899449
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General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies
Epitope AA 2-71
(18), (11), (11), (10), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(147), (104), (41), (5), (2), (2), (2), (2), (1)
Host Goat
(91), (71), (60), (2)
Clonality
Polyclonal
Conjugate This TNFRSF13C antibody is un-conjugated
(19), (12), (12), (8), (8), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
(123), (85), (65), (44), (41), (13), (9), (9), (7), (5), (4), (3), (3), (3), (1), (1), (1)
Pubmed 12 references available
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Product Details anti-TNFRSF13C Antibody

Target Details TNFRSF13C Application Details Handling ProductDetails: References for anti-TNFRSF13C antibody (ABIN4899449) Images
Specificity Detects human BAFF R in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5 % cross-reactivity with recombinant mouse BAFF R and less than 2 % cross-reactivity with recombinant human (rh) 4-1BB, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFas, rhGITR, rhHVEM, rhNGF R, rhOPG, rhRANK, rhTNF RI, and rhTNF RII is observed.
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen Mouse myeloma cell line NS0-derived recombinant human BAFF R/TNFRSF13C, Arg2-Ala71, Accession # Q96RJ3
Isotype IgG

Target Details TNFRSF13C

Product Details anti-TNFRSF13C Antibody Application Details Handling ProductDetails: References for anti-TNFRSF13C antibody (ABIN4899449) Images back to top
Antigen
Alternative Name BAFF R/TNFRSF13C (TNFRSF13C Antibody Abstract)
UniProt Q96RJ3
Pathways NF-kappaB Signaling

Application Details

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Handling ProductDetails: References for anti-TNFRSF13C antibody (ABIN4899449) Images back to top
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
Neutralization 3-15 μg/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details ProductDetails: References for anti-TNFRSF13C antibody (ABIN4899449) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

ProductDetails: References for anti-TNFRSF13C antibody (ABIN4899449)

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling Images back to top
Product cited in:

Saulep-Easton, Vincent, Quah, Wei, Ting, Croce, Tam, Mackay: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, 2016 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Maddur, Sharma, Hegde, Stephen-Victor, Pulendran, Kaveri, Bayry: "Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand." in: Nature communications, Vol. 5, pp. 4092, 2014 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Notas, Alexaki, Kampa, Pelekanou, Charalampopoulos, Sabour-Alaoui, Pediaditakis, Dessirier, Gravanis, Stathopoulos, Tsapis, Castanas: "APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 10, pp. 4748-58, 2012 Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Ohmatsu, Sugaya, Miyagaki, Suga, Fujita, Asano, Tada, Kadono, Sato: "BAFF levels are increased in lesional skin and sera in patients with cutaneous T-cell lymphoma." in: The British journal of dermatology, Vol. 167, Issue 2, pp. 359-67, 2012 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Luster, Mukherjee, Carrell, Cho, Gill, Kelly, Garcia, Ward, Oh, Ullrich, Migone, Humphreys: "Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo." in: PLoS ONE, Vol. 7, Issue 10, pp. e47361, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Yeramilli, Knight: "Requirement for BAFF and APRIL during B cell development in GALT." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 10, pp. 5527-36, 2010 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Badr, Borhis, Lefevre, Chaoul, Deshayes, Dessirier, Lapree, Tsapis, Richard: "BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells." in: Blood, Vol. 111, Issue 5, pp. 2744-54, 2008 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Neri, Kumar, Fulciniti, Vallet, Chhetri, Mukherjee, Tai, Chauhan, Tassone, Venuta, Munshi, Hideshima, Anderson, Raje: "Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 19, pp. 5903-9, 2007 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ettinger, Sims, Robbins, Withers, Fischer, Grammer, Kuchen, Lipsky: "IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 5, pp. 2872-82, 2007 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Elsawa, Novak, Grote, Ziesmer, Witzig, Kyle, Dillon, Harder, Gross, Ansell: "B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia." in: Blood, Vol. 107, Issue 7, pp. 2882-8, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ogden, Pound, Batth, Owens, Johannessen, Wood, Gregory: "Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 5, pp. 3015-23, 2005 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Moir, Malaspina, Pickeral, Donoghue, Vasquez, Miller, Krishnan, Planta, Turney, Justement, Kottilil, Dybul, Mican, Kovacs, Chun, Birse, Fauci: "Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily." in: The Journal of experimental medicine, Vol. 200, Issue 7, pp. 587-99, 2004 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Images

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling ProductDetails: References for anti-TNFRSF13C antibody (ABIN4899449) back to top
Supplier Images
Neutralization (Neut) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 2-71) antibody (ABIN4899449) BAFF R/TNFRSF13C Inhibition of BAFF/BLys/ TNFSF13B-dependent Cell Proliferation and N...
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 2-71) antibody (ABIN4899449) Detection of BAFF R/TNFRSF13C in PBMCs by Flow Cytometry. Peripheral blood mononuclea...
Neutralization (Neut) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 2-71) antibody (ABIN4899449) BAFF R/TNFRSF13C Inhibition of BAFF/BLys/ TNFSF13B-dependent Cell Proliferation and N...
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 2-71) antibody (ABIN4899449) Detection of BAFF R/TNFRSF13C in PBMCs by Flow Cytometry. Peripheral blood mononuclea...