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anti-Mouse (Murine) TNFRSF13C antibody for Blocking Reagent

Recommended TNFRSF13C Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies
  • 2010006P15Rik
  • BAFF-R
  • Baffr
  • BAFFR
  • Bcmd
  • Bcmd-1
  • Bcmd1
  • BROMIX
  • CD268
  • CVID4
  • Lvis22
  • prolixin
  • RGD1560810
  • TNFRSF13C
Reactivity
Mouse (Murine)
129
62
31
4
Host
Rat
86
59
27
Clonality
Monoclonal
Conjugate
This TNFRSF13C antibody is un-conjugated
18
12
10
8
4
4
4
3
2
1
1
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Immunohistochemistry (IHC)
78
73
50
25
21
11
10
7
7
5
4
2
2
1
1
1
1
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Catalog No. ABIN2664464
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Top referenced anti-TNFRSF13C antibody for Blocking Reagent

Similar anti-TNFRSF13C Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 1 Antibodies
ELISA 8 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 28 Antibodies
Functional Studies (Func) 8 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 9 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Neutralization (Neut) 4 Antibodies
Western Blotting (WB) 25 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies
Reactivity Mouse (Murine)
(129), (62), (31), (4)
Host Rat
(86), (59), (27)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF13C antibody is un-conjugated
(18), (12), (10), (8), (4), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Immunohistochemistry (IHC)
(78), (73), (50), (25), (21), (11), (10), (7), (7), (5), (4), (2), (2), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-TNFRSF13C Antibody

Target Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2664464) Images
Purification The antibody was purified by affinity chromatography.
Clone 7H22-E16
Isotype IgG1 kappa

Target Details TNFRSF13C

Product Details anti-TNFRSF13C Antibody Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2664464) Images back to top
Antigen
Alternative Name CD268 (TNFRSF13C Antibody Abstract)
Background BAFF (B cell-activating factor belonging to the TNF family) receptor (BAFF-R) is one of the three receptors that bind to BAFF. It is a type III transmembrane TNF receptor family member. BAFF-R is expressed at high levels in resting B cells and at lower levels in activated B cells, a small subset of activated/memory CD4+ T cells. It is a major mediator of BAFF dependent co-stimulatory response in peripheral B and T cells. It was reported that the mice expressing defective BAFF-R have disrupted B cell maturation. BAFF receptor appears to be particularly important for the regulation of normal B cell survival and maturation, as well as in the pathophysiology of aggressive B-cell malignancies and autoimmune diseases.
Pathways NF-kappaB Signaling

Application Details

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Handling References for anti-TNFRSF13C Antibody (ABIN2664464) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details References for anti-TNFRSF13C Antibody (ABIN2664464) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TNFRSF13C Antibody (ABIN2664464)

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling Images back to top
Background publications

Fu, Lin-Lee, Pham, Tamayo, Yoshimura, Ford: "BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells." in: Blood, Vol. 113, Issue 19, pp. 4627-36, 2009

Ng, Ng, Woehl, Sutherland, Huo, Xu, Mackay, Lam: "BAFF costimulation of Toll-like receptor-activated B-1 cells." in: European journal of immunology, Vol. 36, Issue 7, pp. 1837-46, 2006

Ng, Sutherland, Newton, Qian, Cachero, Scott, Thompson, Wheway, Chtanova, Groom, Sutton, Xin, Tangye, Kalled, Mackay, Mackay: "B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 2, pp. 807-17, 2004

Thompson, Bixler, Qian, Vora, Scott, Cachero, Hession, Schneider, Sizing, Mullen, Strauch, Zafari, Benjamin, Tschopp, Browning, Ambrose: "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF." in: Science (New York, N.Y.), Vol. 293, Issue 5537, pp. 2108-11, 2001

Schiemann, Gommerman, Vora, Cachero, Shulga-Morskaya, Dobles, Frew, Scott: "An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway." in: Science (New York, N.Y.), Vol. 293, Issue 5537, pp. 2111-4, 2001

Batten, Groom, Cachero, Qian, Schneider, Tschopp, Browning, Mackay: "BAFF mediates survival of peripheral immature B lymphocytes." in: The Journal of experimental medicine, Vol. 192, Issue 10, pp. 1453-66, 2000

Images

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2664464) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-TNFRSF13C antibody (Tumor Necrosis Factor Receptor Superfamily, Member 13C) (ABIN2664464) anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) antibody
Flow Cytometry (FACS) image for anti-TNFRSF13C antibody (Tumor Necrosis Factor Receptor Superfamily, Member 13C) (ABIN2664464) anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) antibody (Image 2)