|Application / Reactivity||Rat (Rattus)||Mouse (Murine)|
|ELISA||9 Antibodies||8 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies||1 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies||11 Antibodies|
|Immunohistochemistry (IHC)||8 Antibodies||9 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||8 Antibodies||10 Antibodies|
|Western Blotting (WB)||18 Antibodies|
|Blocking Reagent (BR)||1 Antibodies|
|Flow Cytometry (FACS)||28 Antibodies|
|Functional Studies (Func)||8 Antibodies|
|Intracellular Flow Cytometry (ICFC)||2 Antibodies|
|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This TNFRSF13C antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-TNFRSF13C AntibodyTarget Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN499403) Images
|Specificity||BAFF Receptor antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human BAFF Receptor The peptide sequence is identical between human and mouse origin.|
|Purification||Affinity chromatography purified via peptide column|
|Immunogen||Human BAFF Receptor (C-Terminus) Peptide|
Target Details TNFRSF13CProduct Details anti-TNFRSF13C Antibody Application Details Handling References for anti-TNFRSF13C Antibody (ABIN499403) Images back to top
|Alternative Name||CD268 / BAFFR (TNFRSF13C Antibody Abstract)|
|Background||Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4 (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Two receptors, TACI and BCMA, for BAFF were originally identified (5). A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3 (6,7). Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kB and c-jun N-terminal kinase (4-6).Synonyms: B cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, BR3, TNFRSF13C, Tumor necrosis factor receptor superfamily member 13C|
|Research Area||Apoptosis/Necrosis, Receptors|
Application DetailsProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Handling References for anti-TNFRSF13C Antibody (ABIN499403) Images back to top
ELISA. Western Blot: BAFF Receptor antibody can be used for detection of BAFF Receptor at 2 to 5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details References for anti-TNFRSF13C Antibody (ABIN499403) Images back to top
|Buffer||PBS containing 0.02 % sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store the antibody undiluted at 2-8 °C.|
References for anti-TNFRSF13C Antibody (ABIN499403)Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling Images back to top
Moore, Belvedere, Orr et al.: "BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator." in: Science (New York, N.Y.), Vol. 285, Issue 5425, pp. 260-3, 1999 (PubMed).
Schneider, MacKay, Steiner et al.: "BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth." in: The Journal of experimental medicine, Vol. 189, Issue 11, pp. 1747-56, 1999 (PubMed).
Mukhopadhyay, Ni, Zhai et al.: "Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase." in: The Journal of biological chemistry, Vol. 274, Issue 23, pp. 15978-81, 1999 (PubMed).
Shu, Hu, Johnson: "TALL-1 is a novel member of the TNF family that is down-regulated by mitogens." in: Journal of leukocyte biology, Vol. 65, Issue 5, pp. 680-3, 1999 (PubMed).
ImagesProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN499403) back to top