|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This TNFRSF13C antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-TNFRSF13C AntibodyTarget Details TNFRSF13C Application Details Handling Images
|Specificity||BAFF Receptor antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human BAFF Receptor The peptide sequence is identical between human and mouse origin.|
|Purification||Affinity chromatography purified via peptide column|
|Immunogen||Human BAFF Receptor (C-Terminus) Peptide|
Target Details TNFRSF13CProduct Details anti-TNFRSF13C Antibody Application Details Handling Images back to top
|Alternative Name||CD268 / BAFFR (TNFRSF13C Antibody Abstract)|
|Background||Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4 (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Two receptors, TACI and BCMA, for BAFF were originally identified (5). A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3 (6,7). Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kB and c-jun N-terminal kinase (4-6).Synonyms: B cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, BR3, TNFRSF13C, Tumor necrosis factor receptor superfamily member 13C|
|Research Area||Apoptosis/Necrosis, Receptors|
Application DetailsProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Handling Images back to top
ELISA. Western Blot: BAFF Receptor antibody can be used for detection of BAFF Receptor at 2 to 5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Images back to top
|Buffer||PBS containing 0.02 % sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store the antibody undiluted at 2-8 °C.|