anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Antibodies

ALOX5AP encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Additionally we are shipping ALOX5AP Kits (12) and ALOX5AP Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALOX5AP 11690 P30355
ALOX5AP 29624 P20291
ALOX5AP 241 P20292
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Top anti-ALOX5AP Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185717 (0.1µg/ml) staining of Human U937 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: FLAP Antibody [NBP1-84666] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunohistochemistry-Paraffin: FLAP Antibody [NBP1-84666] - Staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside the reaction centra. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Goat Un-conjugated ELISA, IHC, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Goat Un-conjugated ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: FLAP Antibody [ABIN268657] - Staining of FLAP using ABIN268657 in primary mouse fibroblast cells at 1:500 dilution and counterstained with Hoechst dye. Image courtesy of Lidia Hernandez, NCI Center for Cancer Research Immunohistochemistry-Paraffin: FLAP Antibody  - Staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Dog Goat Un-conjugated EIA, IHC (p), WB Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p) Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ALOX5AP Antibody (Center) (ABIN392385) in K562 cell line lysates (35 µg/lane). ALOX5AP(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated EIA, IHC (p) Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$390.50
Details

Top referenced anti-ALOX5AP Antibodies

  1. Human Polyclonal ALOX5AP Primary Antibody for ELISA, ICC - ABIN268657 : Finkensieper, Kieser, Bekhite, Richter, Mueller, Graebner, Figulla, Sauer, Wartenberg: The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells. in Cardiovascular research 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal ALOX5AP Primary Antibody for IHC, IHC (p) - ABIN4312085 : Perisic, Hedin, Razuvaev, Lengquist, Osterholm, Folkersen, Gillgren, Paulsson-Berne, Ponten, Odeberg, Hedin: Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis. in Arteriosclerosis, thrombosis, and vascular biology 2013 (PubMed)

  3. Human Polyclonal ALOX5AP Primary Antibody for IHC (p), IHC - ABIN251683 : Kaaman, Rydén, Axelsson, Nordström, Sicard, Bouloumié, Langin, Arner, Dahlman: ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance. in International journal of obesity (2005) 2006 (PubMed)

  4. Human Polyclonal ALOX5AP Primary Antibody for IF (p), IHC (p) - ABIN872471 : Elias, Ferré, Vilà, Muñoz, Casellas, Garcia, Molas, Agudo, Roca, Ruberte, Bosch, Franckhauser: ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. in Diabetes 2016 (PubMed)

More Antibodies against ALOX5AP Interaction Partners

Mouse (Murine) Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) interaction partners

  1. ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin (show INS Antibodies) Resistance

  2. Data indicate that a single amino acid mutation was sufficient to reverse the speciation observed in wild type 5-Lipoxygenase activating protein (FLAP).

  3. BRP (show GDF5 Antibodies)-7 potently suppresses leukotriene biosynthesis by interacting with FLAP in mouse peritonitis model.

  4. FLAP regulates phosphorylation of tau protein via modulating GSK-3beta activity.

  5. This study demonistrated that a a novel role for FLAP in the pathogenesis of anxiety-like behavior in mice.

  6. Deletion of myeloid cell FLAP markedly attenuates the proliferative response to vascular injury, while preserving endothelial integrity.

  7. A FLAP inhibitor given during critical window periods may prevent oxygen induced aberration of pulmonary alveolarization in a dose- and time-dependent manner.

  8. the 5-LO (show ALOX5 Antibodies) pathway emerges early during embryonic stem cell differentiation into cells of the myeloid lineage

  9. Adipose tissue from obese mice, compared with that from lean mice, exhibited increased 5-LO (show ALOX5 Antibodies) activating protein

  10. Data show that 5-lipoxygenase (show ALOX5 Antibodies) activity increases during senescence-like growth arrest via a p53 (show TP53 Antibodies)/p21 (show D4S234E Antibodies)-dependent pathway in both human and mouse embryo fibroblasts.

Human Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) interaction partners

  1. This meta-analysis indicates that ALOX5AP rs17222919-1316T/G may be a protective factor against stroke.

  2. Indicate a potential protective role of ALOX5AP and 5-arachidonate lipoxygenase gene in diabetes type 2 pathogenesis.

  3. No significant association was found between ALOX5AP rs10507391 polymorphism and ischemic stroke risk in males. Moreover, ALOX5AP rs10507391 polymorphism was not associated with cardioembolic ischemic stroke risk.

  4. rs17222919 of ALOX5AP is a potential genetic protective factor against ischemic stroke in the Chinese population

  5. This study revealed that epistatic interaction among the ALOX5 (show ALOX5 Antibodies), ALOX5AP and MPO (show MPO Antibodies) genes played a significant role in vulnerability to ischemic stroke.

  6. The results the study indicate that SNP genetic variants of ALOX5AP might play a role in the development of SSc (show CYP11A1 Antibodies)-related pulmonary fibrosis and ventilatory dysfunction.

  7. The observation that the coexpression of FLAP with a subset of the 5-LOX (show ALOX5 Antibodies) mutants restores 5-LOX (show ALOX5 Antibodies)-wild-type (wt)-like levels of products formed in intact cells suggests a physical protein-protein interaction, beyond colocalization, of 5-LOX (show ALOX5 Antibodies) and FLAP.

  8. Meta-analysis suggests that the A allele at the ALOX5AP SG13S114 polymorphism is a protective factor for the ischemic stroke in the European population

  9. Genetic polymorphisms of T-1131C APOA5 (show APOA5 Antibodies) and ALOX5AP SG13S114 can be considered risk factors for the susceptibility to ischemic stroke in Morocco.

  10. Data indicate that a single amino acid mutation was sufficient to reverse the speciation observed in wild type 5-Lipoxygenase activating protein (FLAP).

Cow (Bovine) Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) interaction partners

  1. ALOX5AP, CPNE3 (show CPNE3 Antibodies), IL1R2 (show IL1R2 Antibodies), IL6 (show IL6 Antibodies), TLR2, TLR4 (show TLR4 Antibodies), and THY1 (show THY1 Antibodies) were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.

ALOX5AP Antigen Profile

Protein Summary

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with ALOX5AP

  • arachidonate 5-lipoxygenase-activating protein (alox5ap) antibody
  • arachidonate 5-lipoxygenase activating protein (ALOX5AP) antibody
  • arachidonate 5-lipoxygenase activating protein (alox5ap) antibody
  • arachidonate 5-lipoxygenase activating protein (Alox5ap) antibody
  • al5ap antibody
  • ALOX5AP antibody
  • fj65d02 antibody
  • FLAP antibody
  • wu:fj65d02 antibody
  • zgc:63982 antibody

Protein level used designations for ALOX5AP

arachidonate 5-lipoxygenase-activating protein , Arachidonate 5-lipoxygenase-activating protein , MK-886-binding protein , arachidonate 5 lipoxygenase activating protein , 5-lipoxygenase-activating protein FLAP , FLAP , arachidonate 5-lipoxygenase activating protein , 5-lipoxygenase-activating protein

GENE ID SPECIES
337376 Danio rerio
452520 Pan troglodytes
477323 Canis lupus familiaris
613083 Xenopus (Silurana) tropicalis
770904 Gallus gallus
100286557 Salmo salar
100305320 Oncorhynchus mykiss
100009413 Oryctolagus cuniculus
443326 Ovis aries
11690 Mus musculus
29624 Rattus norvegicus
241 Homo sapiens
613869 Bos taurus
100034178 Equus caballus
397392 Sus scrofa
713170 Macaca mulatta
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