anti-Centromere Protein B (CENPB) Antibodies

CENPB product is a highly conserved protein that facilitates centromere formation. Additionally we are shipping Centromere Protein B Kits (47) and Centromere Protein B Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CENPB 1059 P07199
CENPB 12616 P27790
CENPB 362217  
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Top anti-Centromere Protein B Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CENPB Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC 0.1 mL Log in to see 7 to 9 Days
$587.60
Details
Human Rabbit Un-conjugated IP, WB Western Blot analysis of CENPB expression in transfected 293T cell line by CENPB MaxPab polyclonal antibody.Lane 1: CENPB transfected lysate(65.20 KDa).Lane 2: Non-transfected lysate. Immunoprecipitation of CENPB transfected lysate using anti-CENPB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with CENPB purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 11 to 12 Days
$350.67
Details
Human Rabbit Un-conjugated WB Western Blot: CENPB Antibody [NBP1-58103] - Jurkat cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$488.73
Details
Human Rabbit Un-conjugated ICC, IF CENP-B pAb tested by immunofluorescence. Staining of HeLa cells with CENP-B pAb at a 1 µg/ml dilution (green) and α-tubulin (red, Catalog No. 39527) at 1 µg/ml. 100 μg Log in to see 1 to 2 Days
$507.50
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of CENPB expression in transfected 293T cell line by CENPB MaxPab polyclonal antibody.Lane1:CENPB transfected lysate(65.89 KDa).Lane2:Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to CENPB on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 11 to 12 Days
$364.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB   100 μg Log in to see 13 to 16 Days
$332.00
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details

More Antibodies against Centromere Protein B Interaction Partners

Human Centromere Protein B (CENPB) interaction partners

  1. Given that CENP-B is the only centromere protein that binds centromere-specific DNA elements, our study provides a new link between centromere DNA and unique epigenetic landscape of centromere chromatin

  2. Upon cross-linking, the entire CENPA/CENPB/CENPC/CENPT complex is nuclease-protected over an alpha-satellite dimer that comprises the fundamental unit of centromeric chromatin. We conclude that CENPA/CENPC and CENPT pathways for kinetochore assembly are physically integrated over young alpha-satellite dimers.

  3. Findings indicate that expression of the scleroderma autoantigens IFI-16 and CENPs, which are associated with severe vascular disease, is increased in vascular progenitors and mature endothelial cells. High level, lineage-enriched expression of autoantigens may explain the striking association between clinical phenotypes and the immune targeting of specific autoantigens.

  4. The results indicated that CENPB boxes are highly conserved in Down syndrome (DS) patients and may not be responsible for Chr21 nondisjunction events. However, alphasatDNA in Chr21 is variable and deoxynucleotide deletions, mutations and polymorphisms may act as potential molecular diagnostic markers of DS.

  5. CENP-B directly binds both CENP-A's amino-terminal tail and CENP-C, a key nucleator of kinetochore assembly

  6. The results revealed that CENP-B binding in the vicinity of the CENP-A nucleosome substantially stabilizes the CENP-A nucleosome on alphoid DNA in human cells.

  7. Centromere protein B (CENP-B) as a novel interacting partner of HBZ.

  8. INMAP as a model regulator of CENP-B

  9. N-terminal methylation is required for CENP-B's binding to the CENP-B box.

  10. Human Nap1, an acidic histone chaperone, inhibited the non-specific binding of CENP-B to nucleosomes and apparently stimulated CENP-B binding to its cognate CENP-B box DNA.

  11. CENP-A and/or B status is predictive of the extent of skin involvement over time in systemic sclerosis.

  12. Anti-CENP-B autoantibodies in breast cancer patients prolong disease-free and overall survival.

  13. CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells

  14. crystal structure of its dimerization domain (CENP-B-(540-599)), another functional domain of CENP-B, at 1.65-A resolution

  15. the interaction between CENP-B and CENP-C may be involved in the correct assembly of CENP-C on alphoid DNA

  16. CENP-B for the CENP-B box DNA is reduced nearly to the level of nonspecific DNA binding by CpG methylation

  17. CENP-B may be a determinant for translational positioning of the centromere-specific nucleosomes through its binding to the nucleosomal CENP-B box

  18. This study shows that ICP0 induces the proteasomal-dependent degradation of the centromeric protein CENP-B in infected as well as ICP0-expressing cells.

  19. CENP-B was found to bind specifically to the surface of human pulmonary artery smooth muscle cells and not to fibroblasts or endothelial cells

  20. observation of FRET between CENP-A and CENP-B at centromere locations; this indicates that these proteins are in the molecular vicinity (<10 nm) of each other

Mouse (Murine) Centromere Protein B (CENPB) interaction partners

  1. demonstrate a novel ADA3 interaction with CENP-B-centromere that may account for its previously known function in mitosis

  2. Cenpa, Cenpb, and Bub3, but not Cenpc, interacted with PARP-1

  3. This study shows that ICP0 induces the proteasomal-dependent degradation of the centromeric protein CENP-B in infected as well as ICP0-expressing cells.

  4. Propose that CENP-B plays a dual role in centromere formation, ensuring de novo formation on DNA lacking a functional centromere but preventing the formation of excess centromeres on chromosomes.

Centromere Protein B (CENPB) Antigen Profile

Protein Summary

This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.

Gene names and symbols associated with CENPB

  • centromere protein B (CENPB) antibody
  • centromere protein B (Cenpb) antibody
  • centromere protein B, 80kDa (Cenpb) antibody
  • CENP-B antibody
  • CENPB antibody

Protein level used designations for CENPB

CENP-B , centromere autoantigen B , major centromere autoantigen B , CENP-B protein , centromere protein B , Major centromere autoantigen B , centromere autoantigen protein B , centromere protein B, 80kDa , LOW QUALITY PROTEIN: major centromere autoantigen B

GENE ID SPECIES
1059 Homo sapiens
12616 Mus musculus
362217 Rattus norvegicus
443351 Ovis aries
485791 Canis lupus familiaris
788381 Bos taurus
100356278 Oryctolagus cuniculus
100689274 Cricetulus griseus
100146426 Equus caballus
100622502 Sus scrofa
100713491 Cavia porcellus
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