anti-Centromere Protein B (CENPB) Antibodies

CENPB product is a highly conserved protein that facilitates centromere formation. Additionally we are shipping Centromere Protein B Kits (48) and Centromere Protein B Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CENPB 1059 P07199
CENPB 12616 P27790
CENPB 362217  
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Top anti-Centromere Protein B Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-CENPB Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC 0.1 mL Log in to see 7 to 9 Days
$585.06
Details
Human Rabbit Un-conjugated IP, WB Western Blot analysis of CENPB expression in transfected 293T cell line by CENPB MaxPab polyclonal antibody.<br><br>Lane 1: CENPB transfected lysate(65.20 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunoprecipitation of CENPB transfected lysate using anti-CENPB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with CENPB purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 11 to 12 Days
$425.71
Details
Human Rabbit Un-conjugated WB Western Blot: CENPB Antibody [NBP1-58103] - Jurkat cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated ICC, IF CENP-B pAb tested by immunofluorescence. Staining of HeLa cells with CENP-B pAb at a 1 µg/ml dilution (green) and α-tubulin (red, Catalog No. 39527) at 1 µg/ml. 100 μg Log in to see 1 to 2 Days
$495.83
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of CENPB expression in transfected 293T cell line by CENPB MaxPab polyclonal antibody.<br><br>Lane1:CENPB transfected lysate(65.89 KDa).<br>Lane2:Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to CENPB on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB   100 μg Log in to see 13 to 16 Days
$332.00
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details

More Antibodies against Centromere Protein B Interaction Partners

Human Centromere Protein B (CENPB) interaction partners

  1. Given that CENP-B is the only centromere protein that binds centromere-specific DNA elements, our study provides a new link between centromere DNA and unique epigenetic landscape of centromere chromatin

  2. Upon cross-linking, the entire CENPA (show CENPA Antibodies)/CENPB/CENPC (show CENPC1 Antibodies)/CENPT (show CENPT Antibodies) complex is nuclease (show DCLRE1C Antibodies)-protected over an alpha-satellite dimer that comprises the fundamental unit of centromeric chromatin. We conclude that CENPA/CENPC (show CENPA Antibodies) and CENPT (show CENPT Antibodies) pathways for kinetochore assembly are physically integrated over young alpha-satellite dimers.

  3. Findings indicate that expression of the scleroderma autoantigens IFI-16 (show IFI16 Antibodies) and CENPs (show APITD1 Antibodies), which are associated with severe vascular disease, is increased in vascular progenitors and mature endothelial cells. High level, lineage-enriched expression of autoantigens may explain the striking association between clinical phenotypes and the immune targeting of specific autoantigens.

  4. The results indicated that CENPB boxes are highly conserved in Down syndrome (DS) patients and may not be responsible for Chr21 nondisjunction events. However, alphasatDNA in Chr21 is variable and deoxynucleotide deletions, mutations and polymorphisms may act as potential molecular diagnostic markers of DS.

  5. CENP-B directly binds both CENP-A's amino-terminal tail and CENP-C (show CENPC1 Antibodies), a key nucleator of kinetochore assembly

  6. The results revealed that CENP-B binding in the vicinity of the CENP-A (show CENPA Antibodies) nucleosome substantially stabilizes the CENP-A (show CENPA Antibodies) nucleosome on alphoid DNA in human cells.

  7. Centromere protein B (CENP-B) as a novel interacting partner of HBZ (show HBZ Antibodies).

  8. INMAP as a model regulator of CENP-B

  9. N-terminal methylation is required for CENP-B's binding to the CENP-B box.

  10. Human Nap1 (show IL8 Antibodies), an acidic histone chaperone, inhibited the non-specific binding of CENP-B to nucleosomes and apparently stimulated CENP-B binding to its cognate CENP-B box DNA.

Mouse (Murine) Centromere Protein B (CENPB) interaction partners

  1. demonstrate a novel ADA3 (show TADA3 Antibodies) interaction with CENP-B-centromere that may account for its previously known function in mitosis

  2. Cenpa (show CENPA Antibodies), Cenpb, and Bub3 (show BUB3 Antibodies), but not Cenpc (show CENPC1 Antibodies), interacted with PARP-1 (show PARP1 Antibodies)

  3. This study shows that ICP0 induces the proteasomal-dependent degradation of the centromeric protein CENP-B in infected as well as ICP0-expressing cells.

  4. Propose that CENP-B plays a dual role in centromere formation, ensuring de novo formation on DNA lacking a functional centromere but preventing the formation of excess centromeres on chromosomes.

Centromere Protein B (CENPB) Antigen Profile

Protein Summary

This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.

Gene names and symbols associated with CENPB

  • centromere protein B (CENPB) antibody
  • centromere protein B (Cenpb) antibody
  • centromere protein B, 80kDa (Cenpb) antibody
  • CENP-B antibody
  • CENPB antibody

Protein level used designations for CENPB

CENP-B , centromere autoantigen B , major centromere autoantigen B , CENP-B protein , centromere protein B , Major centromere autoantigen B , centromere autoantigen protein B , centromere protein B, 80kDa , LOW QUALITY PROTEIN: major centromere autoantigen B

GENE ID SPECIES
1059 Homo sapiens
12616 Mus musculus
362217 Rattus norvegicus
443351 Ovis aries
485791 Canis lupus familiaris
788381 Bos taurus
100356278 Oryctolagus cuniculus
100689274 Cricetulus griseus
100146426 Equus caballus
100622502 Sus scrofa
100713491 Cavia porcellus
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