anti-Desmoglein 3 (DSG3) Antibodies

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Additionally we are shipping Desmoglein 3 Kits (21) and Desmoglein 3 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DSG3 1830 P32926
DSG3 13512  
DSG3 291752  
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Top anti-Desmoglein 3 Antibodies at antibodies-online.com

Showing 10 out of 230 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ICC, FACS, IF, IHC (p), IP, IHC, WB 0.1 mL Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated WB Western blot analysis of Desmoglein 3 expression in A431 (A), HeLa (B), Raw264.7 (C), PC12 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: Desmoglein-3 Antibody (5H10) [NBP1-78984] - Analysis of Desmoglein 3 expression in HaCat cell lysate using NBP1-78984. Immunohistochemistry: Desmoglein-3 Antibody (5H10) [NBP1-78984] - Analysis of Desmoglein 3 on human skin cancer using NBP1-78984. 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Human Mouse Un-conjugated ELISA, FACS, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using DSG3 mAb against human DSG3 (AA: 55-159) recombinant protein. (Expected MW is 37.5 kDa) Dilution: 1/500 - 1/2000 100 μL Log in to see 8 to 11 Days
$561.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Desmoglein-3 Antibody (N-term) in WiDr cell line lysates (35ug/lane). This demonstrates the DSG3 antibody detected the DSG3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated CyTOF, ELISA, FACS, IHC, WB ELISA: Desmoglein-3 Antibody (6G2C11) [NBP2-37259] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); Immunohistochemistry: Desmoglein-3 Antibody (6G2C11) [NBP2-37259] - Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using DSG3 mouse mAb with DAB staining. 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: Desmoglein-3 Antibody  - Staining of human esophagus shows strong membranous and cytoplasmic positivity in squamous epithelial cells. Immunohistochemistry-Paraffin: Desmoglein-3 Antibody  - Staining of human esophagus shows high expression. 100 μL Log in to see 10 to 13 Days
$491.63
Details
Human Mouse Un-conjugated IHC (fro), WB   5 mL Log in to see 6 to 8 Days
$357.50
Details
Human Rabbit Un-conjugated WB Anti-Desmoglein 3 antibody, Western blotting Lane 1: A431 Cell Lysate Lane 2: CEM Cell Lysate 100 μg Log in to see 4 to 6 Days
$240.00
Details

Top referenced anti-Desmoglein 3 Antibodies

  1. Human Monoclonal Desmoglein 3 Primary Antibody for ICC, IF - ABIN4305016 : Proby, Ota, Suzuki, Koyasu, Gamou, Shimizu, Wahl, Wheelock, Nishikawa, Amagai: Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris. in The British journal of dermatology 2000 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal Desmoglein 3 Primary Antibody for ICC, FACS - ABIN151179 : Wu, Stanley, Cotsarelis: Desmoglein isotype expression in the hair follicle and its cysts correlates with type of keratinization and degree of differentiation. in The Journal of investigative dermatology 2003 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal Desmoglein 3 Primary Antibody for IHC (fro), IP - ABIN2473333 : Smith, Richards, Yasin, Sangster, Sridaran: Changes in rat luteal ultrastructure and P450scc mRNA and protein content after in vivo treatment with a gonadotropin-releasing hormone agonist. in Biology of reproduction 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal Desmoglein 3 Primary Antibody for FACS, IF - ABIN5576864 : Mahoney, Hu, Brennan, Bazzi, Christiano, Wahl: Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseases. in Experimental dermatology 2006 (PubMed)

More Antibodies against Desmoglein 3 Interaction Partners

Human Desmoglein 3 (DSG3) interaction partners

  1. flotillin (show FLOT2 Antibodies) has a role in desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes

  2. our findings suggest that Dsg3 functions as a key in cell-cell adhesion through at least a mechanism of regulating E-cadherin (show CDH1 Antibodies) membrane trafficking

  3. Desmoglein 3 Order and Dynamics in Desmosomes

  4. Data indicate that all 3 monoclonal antibodies (mAbs) targeted the same extracellular cadherin (EC) domain on desmoglein 3 (Dsg3), caused Dsg3 internalization in primary keratinocytes, and caused suprabasal blisters in skin.

  5. DSG3 was a key prognostic factor and predictor for neoadjuvant concurrent chemoradiotherapy response in rectal cancer patients.

  6. Treg cells exert a clear down-regulatory effect on the Dsg3-driven T-cell response and, accordingly, the formation of Dsg3-specific IgG antibodies

  7. Data identify DSG3 as a negative prognostic biomarker in resected pancreatic ductal adenocarcinoma, as high DSG3 expression is associated with poor overall survival and poor tumour-specific survival.

  8. this study directly demonstrates the occurrence of desmoglein 3 molecules outside of desmosomes and reveales that the adhesive properties of these molecules do differ depending on their localization.

  9. DSG2 (show DSG2 Antibodies) and DSG3 might be potential diagnostic markers for squamous cell carcinoma of the lung and DSG3 could be a potential differentiation marker for lung cancer.

  10. alterations of their expression suggest a role of Dsg3 and gamma-catenin (show JUP Antibodies) (additionally to E-cadherin (show CDH1 Antibodies)/beta-catenin (show CTNNB1 Antibodies)) as biomarkers of malignant transformation risk of oral dysplasia and the biological behavior (aggressiveness) of oral cancer, respectively

Mouse (Murine) Desmoglein 3 (DSG3) interaction partners

  1. flotillin (show FLOT2 Antibodies) has a role in desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes

  2. Desmoglein 3 deficiency in mice leads to a phenotype characterized by cyclic alopecia in addition to the dramatic skin and mucocutaneous acantholysis observed in pemphigus patients.

  3. Dsg3, via p38 MAPK (show MAPK14 Antibodies), regulates the spatial distribution of the keratin filament network and stabilizes cell adhesion.

  4. Squamous metaplasia after pulmonary epithelial injury may play a crucial role in redirecting the skin-specific autoimmune reaction to the lungs in paraneoplastic pemphigus (PNP (show NP Antibodies)).

  5. Dsg3 deficiency results in perturbation of the desmosomal network at the transcriptional, translational, and interaction level, kinase activation, proteinase-mediated degradation, and hyper-adhesion. (Review)

  6. Thus, Dsg3 does not display a clear function as a tumor suppressor in these mouse skin cancer models

  7. IgG and IgM (show CD40LG Antibodies) antibodies against desmoglein 3 have a pathogenic role in blister formation in pemphigus vulgaris

  8. the adult passive transfer mouse model is ideally suited for detailed studies of Dsg3 antibody-mediated signaling in adult skin.

  9. These data indicate a contribution of Dsg (show DSG1 Antibodies) depletion to pemphigus vulgaris pathogenesis dependent on Ca(2 (show CA2 Antibodies)+)-induced differentiation.

  10. Transgenic expression of Dsg1 (show DSG1 Antibodies) rescued the severe B6-Dsg3(-/-) phenotype and provided a syngeneic mouse model of pemphigus vulgaris.

Desmoglein 3 (DSG3) Antigen Profile

Protein Summary

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Gene names and symbols associated with anti-Desmoglein 3 (DSG3) Antibodies

  • desmoglein 3 (DSG3) antibody
  • desmoglein 3 (Dsg3) antibody
  • bal antibody
  • balding antibody
  • CDHF6 antibody
  • DSG3 antibody
  • PVA antibody

Protein level used designations for anti-Desmoglein 3 (DSG3) Antibodies

desmoglein 3 (pemphigus vulgaris antigen) , desmoglein-3 , desmoglein 3 , 130 kDa pemphigus vulgaris antigen , 130-kD pemphigus vulgaris antigen , cadherin family member 6 , pemphigus vulgaris antigen , 130 kDa pemphigus vulgaris antigen homolog , desmoglein 3 preprotein

GENE ID SPECIES
468511 Pan troglodytes
529902 Bos taurus
705685 Macaca mulatta
100347905 Oryctolagus cuniculus
100590729 Nomascus leucogenys
1830 Homo sapiens
13512 Mus musculus
291752 Rattus norvegicus
403470 Canis lupus familiaris
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