Interleukin 27 Proteins (IL27)

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (170) and IL27 Kits (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL27 53342 Q8TAD2
IL27 365368  
IL27 246779 Q8K3I6
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Top IL27 Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
CHO Cells Human His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
Human Cells Mouse His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse Un-conjugated 100 μg Log in to see 1 to 2 Days
$638.00
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$784.00
Details
Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$800.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Mouse Un-conjugated   1 mg Log in to see 2 to 3 Days
$6,760.00
Details
HEK-293 Cells Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$460.00
Details

IL27 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Rat (Rattus)

Mouse (Murine) , ,

Top referenced IL27 Proteins

  1. Human IL27 Protein expressed in Wheat germ - ABIN1307800 : Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 2 Pubmed References

More Proteins for Interleukin 27 (IL27) Interaction Partners

Human Interleukin 27 (IL27) interaction partners

  1. IL-27 was down-regulated in the malignant Middle Cerebral Artery Infarction.

  2. IL-27 may be involved in the development of coronary artery lesions in acute Kawasaki disease.

  3. Hepatitis B virus infection can lead to overexpression of interleukin-27 gene in liver transplant patients.

  4. this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer

  5. IL-27 signaling (IL-27 and its receptor) may be involved in the pathogenesis of HIV infection and immune reconstitution in HIV/AIDS patients who underwent HAART. IL-27 may exert effects through regulating Th1 (show TH1L Proteins) / Th2 ratio.

  6. This study provides additional evidence that IL-27 may contribute to autoimmune processes in MS patients.

  7. this study shows that IL-27 regulates the adherence, proliferation, and migration of placenta-derived mesenchymal stromal cells and enhances their regulatory effects on Th1 (show TH1L Proteins) and Th2 subset generations

  8. This study failed to find an association between common variants in the functional region of IL27 and coronary artery disease in a Chinese Han population

  9. Data point out to a broad set of activities shared by IL-27 and IFN-gamma (show IFNG Proteins), which are dependent on the common activation of the STAT1 (show STAT1 Proteins) pathway. These data add further explanation to the anti-tumor activity of IL-27 and also to its dual role in immune regulation

  10. The current meta-analysis suggests that IL-27 -964A/G polymorphism might enhance cancer risk. However, large-scale and well-designed studies are still needed to confirm the result of our meta-analysis

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. IFN-gamma (show IFNG Proteins) induces IL-30 production which suppresses IFN-gamma (show IFNG Proteins) mediated liver inflammation.

  2. IL-27 signaling in Foxp3 (show FOXP3 Proteins)(+) Tregs essential for Tregs to control autoimmune inflammation in the central nervous system

  3. this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer

  4. this study has revealed an important role of thymic dendritic cells-derived IL-27 in the regulation of the phenotypic maturation of CD4 (show CD4 Proteins)(+) single positive thymocytes.

  5. TTP (show ZFP36 Proteins), encoded by Zfp36 (show ZFP36 Proteins), degrades p28 (show GSTO1 Proteins) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.

  6. these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (show TXNRD1 Proteins)-like cells in celiac disease

  7. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (show TP53 Proteins) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  8. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (show LTF Proteins).

  9. Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS (show TLR4 Proteins) injection compared with control specimens.

  10. these findings highlight critical roles for IFN-gamma (show IFNG Proteins) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 Protein Profile

Protein Summary

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with Interleukin 27 Proteins (IL27)

  • interleukin 17D (IL17D)
  • interleukin 27 (IL27)
  • interleukin 27 (Il27)
  • IL-17D protein
  • IL-22 protein
  • IL-27 protein
  • IL-27A protein
  • IL-27p28 protein
  • IL27 protein
  • IL27A protein
  • IL27p28 protein
  • Il30 protein
  • p28 protein
  • RGD1561420 protein

Protein level used designations for Interleukin 27 Proteins (IL27)

interleukin 27 , interleukin-17D , interleukin-27 , IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interluekin 27 , interleukin 27 p28 subunit , p28

GENE ID SPECIES
53342 Homo sapiens
246778 Homo sapiens
365368 Rattus norvegicus
607880 Canis lupus familiaris
614927 Bos taurus
737725 Pan troglodytes
246779 Mus musculus
493187 Sus scrofa
100349321 Oryctolagus cuniculus
100724612 Cavia porcellus
101122495 Ovis aries
101093822 Felis catus
Selected quality suppliers for IL27 Proteins (IL27)
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