IL1R1 antibody
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- Target See all IL1R1 Antibodies
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
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Reactivity
- Human, Primate
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL1R1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Characteristics
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Synonyms: IL1RT1 antibody, Interleukin 1 receptor alpha type 1 antibody, Interleukin 1 receptor antagonist protein (IRAP) antibody, Antigen CD121a antibody, CD121A antibody, CD121a antigen antibody, D2S1473 antibody, IL 1 antibody, rabbit anti-IL-1 Receptor Type I Antibody, rabbit anti-interleukin-1 Receptor Type I Antibody
Background: IL-1 Receptor Type I is a cytokine receptor which binds interleukin 1. Anti-IL-1 Receptor Type I antibody is ideal for researchers interested in Immunology, Signal Transduction and Cancer.
Gene Name: IL1R1
- Purification
- This antiserum has been heated to 56°C for 30 minutes. The antiserum is directed against the extracellular domain of the human IL-1R type I, but precipitates the intact receptor expressed on human cells. In general, this antibody also detects primate IL-1RI. The antibody does not recognize human IL-1, IL-1Ra or IL-1R type II. In ELISA formats and other immunoreactive assays, this antibody will detect the extracellular domain of the IL-1R type I (also called soluble IL-1R type I or ''decoy'' receptor) found in human body fluids, particularly in the circulation, urine and supernatants of cells and synovial fluid.
- Immunogen
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Immunogen: IL-1 Receptor Type I Antibody was prepared by repeated immunizations with recombinant human IL-1R type I.
Immunogen Type: Recombinant Protein
- Top Product
- Discover our top product IL1R1 Primary Antibody
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- Application Notes
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Flow Cytometry Dilution: User Optimized
Immunohistochemistry Dilution: User Optimized
Application Note: This antiserum against anti-Human IL-1 Receptor Type I (IL-1RI) has been tested for use in ELISA, radioimmunoassays and immunoprecipitation. Reactivity in other immunoassays is unknown.This product has been assayed for the ability to immunoprecipitate antigen. A dilution range of 1:400 to 1:800 is suggested for this immunoassay. For immunoprecipitation, pre-clearing with a non-specific rabbit IgG is helpful to reduce background. This product has been assayed by ELISA against soluble (extracellular) IL-1RI using HRP Conjugated Anti-Rabbit IgG [H&L] (Goat) (code # 611-1302) and ABTS as a substrate for 30 minutes at room temperature. A working dilution range of 1:1,000 to 1:2000 is suggested for this product. This product has been assayed by radioimmunoassay against antigen. A dilution of 1:8,000 is suggested for this immunoassay.
Neutralization Dilution: User Optimized
Western Blot Dilution: User Optimized
Immunoprecipitation Dilution: User Optimized
ELISA Dilution: User Optimized
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 84 mg/mL
- Buffer
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 12 months
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Alternative Name
- IL-1 Receptor Type I (IL1R1 Products)
- Synonyms
- CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody
- Gene ID
- 3554
- UniProt
- P14778
- Pathways
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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