RPS6KB2 antibody (AA 281-380) (Alexa Fluor 350)
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- Target See all RPS6KB2 Antibodies
- RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))
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Binding Specificity
- AA 281-380
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RPS6KB2 antibody is conjugated to Alexa Fluor 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human p70 S6 kinase beta
- Isotype
- IgG
- Top Product
- Discover our top product RPS6KB2 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))
- Alternative Name
- p70 S6 kinase beta (RPS6KB2 Products)
- Synonyms
- KLS antibody, P70-beta antibody, P70-beta-1 antibody, P70-beta-2 antibody, S6K-beta2 antibody, S6K2 antibody, SRK antibody, STK14B antibody, p70(S6K)-beta antibody, p70S6Kb antibody, 70kDa antibody, ribosomal protein S6 kinase B2 antibody, ribosomal protein S6 kinase, polypeptide 2 antibody, RPS6KB2 antibody, Rps6kb2 antibody
- Background
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Synonyms: 70 kDa ribosomal protein S6 kinase 1, P70 S6K, P70 S6 Kinase beta, KS6B1_HUMAN, p70 alpha, P70 beta 1, P70 beta 1, p70 ribosomal S6 kinase alpha, p70 ribosomal S6 kinase beta 1, p70 ribosomal S6 kinase beta 1, p70 S6 kinase alpha, P70 S6 Kinase, p70 S6 kinase, alpha 1, p70 S6 kinase, alpha 2, p70 S6K, p70 S6K-alpha, p70 S6KA, p70S6K alpha, p70S6K-alpha, p70-alpha, p70-S6K 1, p70-S6K, P70S6K, P70S6K1, p70S6Kb, p70S6Kb, PS6K, Ribosomal protein S6 kinase 70 kDa polypeptide 1, Ribosomal protein S6 kinase 70 kDa polypeptide 2, Ribosomal protein S6 kinase 70 kDa polypeptide 2, Ribosomal protein S6 kinase beta 1, Ribosomal protein S6 kinase beta-1, Ribosomal protein S6 kinase I, RPS6KB1, RPS6KB2, RPS6KB2, S6K, S6K-beta-1, S6K1, Serine/threonine kinase 14 alpha, Serine/threonine-protein kinase 14A, STK14A.
Background: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].
- Gene ID
- 6199
- Pathways
- PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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