IL1R1 antibody (pTyr496)

Catalog No. ABIN1450326

Product Details anti-IL1R1 Antibody

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Binding Specificity: AA 471-520, pTyr496

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1R1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity:

IL-1Ralpha/CD121alpha (Phospho-Tyr496) Antibody detects endogenous levels of IL-1Ralpha/CD121alpha only when phosphorylated at Tyr496.

PhosphorylationH:Y496, M:Y499, R:Y499

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-1Ralpha/CD121alpha around the phosphorylation site of Tyr496.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for IL1R1

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Abstract: IL1R1 Products

Synonyms: CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody

Background:

Synonyms: Antigen CD121a, IL-1R alpha, IL-1R-1, IL-1R-alpha, IL1R, IL1R1, IL1RA, Interleukin-1 receptor, type I precursor, P80

NCBI Gene Symbol: IL1R1

Molecular Weight: 65 kDa

Gene ID: 3554

OMIM: 147810

UniProt: P14778

Pathways: NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints