GZMB antibody (Biotin)
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- Target See all GZMB Antibodies
- GZMB (Granzyme B (GZMB))
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Reactivity
- Human, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GZMB antibody is conjugated to Biotin
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Application
- ELISA
- Specificity
- Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death. Species cross-reactivity: Human, rhesus monkey, chimpanzee.
- Purification
- Protein A purified
- Immunogen
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Purified human Granzyme B.
Type of Immunogen: Purified protein - Clone
- GB10
- Isotype
- IgG1
- Top Product
- Discover our top product GZMB Primary Antibody
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- Application Notes
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Approved: ELISA (1 μg/mL)
Usage: ELISA: 1 μg/mL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffer saline, 1 % BSA, 0.001 % Thiomersal.
- Handling Advice
- avoid freeze thaw cycles. Store undiluted.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- GZMB / Granzyme B (GZMB Products)
- Synonyms
- CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
- Background
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Name/Gene ID: GZMB
Subfamily: Serine S1
Family: Protease
Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2 - Gene ID
- 3002
- UniProt
- P10144
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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