PDK2 antibody

Catalog No. ABIN2426341

Product Details anti-PDK2 Antibody

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human PDK2

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDK2

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Alternative Name: PDK2 (PDK2 Products)

Synonyms: PDHK2 antibody, PDKII antibody, Pdk antibody, zgc:56209 antibody, PDK2 antibody, pyruvate dehydrogenase kinase 2 antibody, pyruvate dehydrogenase kinase, isoenzyme 2 antibody, pyruvate dehydrogenase kinase, isozyme 2b antibody, PDK2 antibody, Pdk2 antibody, pdk2b antibody

Background: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2,mitochondrial,PDHK2,PDK2,PDK2,Pyruvate dehydrogenase kinase isoform 2,Pyruvate dehydrogenase kinase,isozyme 2,Pyruvate dehydrogenase lipoamide kinase isozyme 2,mitochondrial,This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: Calculated MW: 46 kDa

NCBI Accession: NP_002602

Pathways: PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect