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Metabotropic Glutamate Receptor 5 antibody (AA 824-1203) (Atto 390)

GRM5 Reactivity: Rat WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S75-33 Atto 390
Catalog No. ABIN2483971
  • Target See all Metabotropic Glutamate Receptor 5 (GRM5) Antibodies
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Binding Specificity
    • 39
    • 28
    • 16
    • 15
    • 14
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 824-1203
    Reactivity
    • 107
    • 78
    • 77
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Host
    • 85
    • 43
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 81
    • 51
    Monoclonal
    Conjugate
    • 42
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Metabotropic Glutamate Receptor 5 antibody is conjugated to Atto 390
    Application
    • 112
    • 56
    • 39
    • 33
    • 26
    • 25
    • 19
    • 18
    • 13
    • 13
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificity
    Detects ~130 kDa (both mGluR1 and mGluR5).
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
    Clone
    S75-33
    Isotype
    IgG1
    Top Product
    Discover our top product GRM5 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2483971 was sufficient for detection of mGluR1/5 glutamate receptor in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Alternative Name
    mGluR5 (GRM5 Products)
    Synonyms
    GPRC1E antibody, MGLUR5 antibody, mGlu5 antibody, mGluR5 antibody, mGlur5 antibody, 6430542K11Rik antibody, AI850523 antibody, Glu5R antibody, Gprc1e antibody, mGluR5b antibody, glutamate receptor, metabotropic 5 antibody, glutamate metabotropic receptor 5 antibody, GRM5 antibody, Grm5 antibody
    Background
    The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers (1,2).
    Gene ID
    24418
    NCBI Accession
    NP_058708
    UniProt
    P31424
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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