RUNX2 antibody (AA 244-258)
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- Target See all RUNX2 Antibodies
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Binding Specificity
- AA 244-258
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Monkey, Rabbit, Hamster, Chimpanzee, Gibbon, Orang-Utan, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RUNX2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Human CBFA1 / RUNX2
- Purification
- Immunoaffinity purified
- Immunogen
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A synthetic peptide corresponding to a sequence in the middle region of human RUNX2(244-258aa DRLSDLGRIPHPSMR). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Mouse, Ferret, Sheep, Hamster, Elephant, Rabbit, Horse, Pig, Guinea pig, Dog (100%), Turkey, Sparrow, Chicken, Platypus, Lizard (93%).
Type of Immunogen: Synthetic peptide - Isotype
- IgG
- Top Product
- Discover our top product RUNX2 Primary Antibody
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- Application Notes
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Approved: WB (0.5 - 1 μg/mL)
Usage: Core binding factor A1(CBFA1/RUNX2) is a runt-like transcription factor essential for osteoblast differentiation. This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. D'Souza et al.(1999) indicate a non-redundant role for Cbfa1 in tooth development that may be distinct from that in bone formation. In odontogenesis, Cbfa1 is not involved in the early signaling networks regulating tooth initiation and early morphogenesis but regulates key epithelial-mesenchymal interactions that control advancing morphogenesis and histodifferentiation of the epithelial enamel organ. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Sterile distilled water
- Concentration
- Lot specific
- Buffer
- Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.
- Preservative
- Sodium azide, Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid freeze/thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
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- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Alternative Name
- CBFA1 / RUNX2 (RUNX2 Products)
- Synonyms
- AML3 antibody, CBF-alpha-1 antibody, CBFA1 antibody, CCD antibody, CCD1 antibody, CLCD antibody, OSF-2 antibody, OSF2 antibody, PEA2aA antibody, PEBP2aA antibody, Cbf antibody, Cbfa-1 antibody, Cbfa1 antibody, LS3 antibody, Osf2 antibody, Pebp2a1 antibody, Pebpa2a antibody, runx2 antibody, RUNX2 antibody, ccd antibody, aml3 antibody, ccd1 antibody, osf2 antibody, cbfa1 antibody, pea2aa antibody, pebp2a1 antibody, pebp2a2 antibody, pebp2aa antibody, pebp2aa1 antibody, runt related transcription factor 2 antibody, runt-related transcription factor 2a antibody, runt-related transcription factor 2 antibody, runt related transcription factor 2 L homeolog antibody, RUNX2 antibody, runx2a antibody, Runx2 antibody, runx2 antibody, LOC703331 antibody, LOC100549663 antibody, runx2.L antibody
- Background
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Name/Gene ID: RUNX2
Synonyms: RUNX2, AML3, CCD, CCD1, OSF2, PEBP2A1, PEBP2A2, PEA2-alpha A, PEBP2-alpha A, OSF-2, PEBP2A, PEBP2aA1, CBF-alpha-1, CBFA1, Oncogene AML-3, PEA2aA, PEBP2aA - Gene ID
- 860
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