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GRB2 antibody (AA 89-118)
GRB2
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB15648
unconjugated
Product Details anti-GRB2 Antibody
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Target
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GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Binding Specificity
All epitopes for GRB2 antibodies
AA 89-118
Reactivity
All reactivities for GRB2 antibodies
Human
Host
All hosts for GRB2 antibodies
Rabbit
Clonality
All clonalities for GRB2 antibodies
Polyclonal
Conjugate
All conjugates for GRB2 antibodies
This GRB2 antibody is un-conjugated
Application
All applications for GRB2 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
X, M, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the Central region of human GRB2.
Clone
RB15648
Isotype
Ig Fraction
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Discover our top product GRB2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for GRB2
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Target
GRB2
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Alternative Name
GRB2 (GRB2 Products )
Synonyms
GRB2 antibody, grb2 antibody, AA408164 antibody, Ash antibody, ASH antibody, EGFRBP-GRB2 antibody, Grb3-3 antibody, MST084 antibody, MSTP084 antibody, NCKAP2 antibody, wu:fb18e12 antibody, wu:fb34e06 antibody, zgc:73077 antibody, growth factor receptor bound protein 2 antibody, growth factor receptor-bound protein 2 antibody, growth factor receptor-bound protein 2b antibody, GRB2 antibody, grb2 antibody, Grb2 antibody, grb2b antibody
Background
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences.
Molecular Weight
25206
Gene ID
2885
NCBI Accession
NP_002077 , NP_987102
UniProt
P62993
Pathways
RTK Signaling , TCR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Actin Filament Polymerization , Hepatitis C , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , EGFR Downregulation
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