TEK antibody

Catalog No. ABIN289555

Product Details anti-TEK Antibody

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity: This antibody is specific to human liver Cathepsin H. Does not crossreact with Cathepsin B, Cathepsin D or Cathepsin L.

Cross-Reactivity (Details): This human TIE2 sequence is 100 % conserved in mouse, rat, frog and bovine.

Purification: Affinity chromatography purified

Immunogen: TIE2 antibody was raised in rabbit using a 20 amino acid peptide from human TIE2 as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000-1:100,000, HC: 2-20 µg/mL, IF: 2-20 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from 100 mM Tris, pH 7.5, with 0.2 % BSA, and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for TEK

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Alternative Name: TIE2 (TEK Products)

Synonyms: TEK antibody, DKFZp469E064 antibody, AA517024 antibody, Cd202b antibody, Hyk antibody, Tie2 antibody, tie-2 antibody, CD202B antibody, TIE-2 antibody, TIE2 antibody, VMCM antibody, VMCM1 antibody, Tie-2 antibody, tie2 antibody, TEK receptor tyrosine kinase antibody, angiopoietin-1 receptor antibody, TEK tyrosine kinase, endothelial antibody, TEK antibody, LOC100408334 antibody, tek antibody, Tek antibody

Background: The family of receptor tyrosine kinases TIE1 and TIE 2 or Tek has been identified in vascular endothelium and hematopoietic cells. Ties may represent the earliest endothelial cell lineage marker and may regulate the endothelial cell proliferation, differentiation, and proper patterning during vasculogenesis.

Pathways: RTK Signaling, Growth Factor Binding