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BRAF antibody (AA 38-230)
BRAF
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-BRAF Antibody
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Target
See all BRAF Antibodies
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Binding Specificity
All epitopes for BRAF antibodies
AA 38-230
Reactivity
All reactivities for BRAF antibodies
Human, Mouse, Rat
Host
All hosts for BRAF antibodies
Rabbit
Clonality
All clonalities for BRAF antibodies
Polyclonal
Conjugate
All conjugates for BRAF antibodies
This BRAF antibody is un-conjugated
Application
All applications for BRAF antibodies
Western Blotting (WB)
Purification
Antigen affinity
Immunogen
Human partial recombinant protein (AA 38-230) was used as the immunogen for this BRAF antibody.
Isotype
IgG
Top Product
Discover our top product BRAF Primary Antibody
Alternatives
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Application Details
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Application Notes
Titration of the BRAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Handling
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Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
The lyophilized BRAF antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target Details for BRAF
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Target
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Alternative Name
BRAF (BRAF Products )
Synonyms
B-RAF1 antibody, BRAF1 antibody, NS7 antibody, RAFB1 antibody, C-RMIL antibody, RMIL antibody, B-Raf antibody, braf1 antibody, rafb1 antibody, b-raf1 antibody, sierrabraf antibody, BRAF antibody, 9930012E13Rik antibody, AA120551 antibody, AA387315 antibody, AA473386 antibody, B-raf antibody, Braf-2 antibody, Braf2 antibody, C230098H17 antibody, C87398 antibody, D6Ertd631e antibody, braf antibody, fc48g01 antibody, wu:fc48g01 antibody, B-Raf proto-oncogene, serine/threonine kinase antibody, B-Raf proto-oncogene, serine/threonine kinase S homeolog antibody, Braf transforming gene antibody, si:dkey-222f8.3 antibody, BRAF antibody, Braf antibody, braf.S antibody, braf antibody, si:dkey-222f8.3 antibody
Background
BRAF (v-raf murine sarcoma viral oncogene homolog B1) is a human gene that makes a protein called B Raf. It is a member of the Raf kinase family of growth signal transduction protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. It is mapped to 7q34. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. The BRAF protein is also involved in sending signals inside cells, which are involved in directing cell growth.
Gene ID
673
Pathways
MAPK Signaling , RTK Signaling , Neurotrophin Signaling Pathway , Ribonucleoprotein Complex Subunit Organization , Hepatitis C , Autophagy
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