RPS6KB2 antibody (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2) (AA 389-438)

Details for Product anti-RPS6KB2 Antibody No. ABIN482681, Supplier: Log in to see
Antigen
  • KLS
  • P70-beta
  • P70-beta-1
  • P70-beta-2
  • S6K-beta2
  • S6K2
  • SRK
  • STK14B
  • p70(S6K)-beta
  • p70S6Kb
  • 70kDa
  • ribosomal protein S6 kinase B2
  • ribosomal protein S6 kinase, polypeptide 2
  • RPS6KB2
  • Rps6kb2
Alternatives
anti-Human RPS6KB2 antibody for Immunoprecipitation
Epitope
AA 389-438, pSer423
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Reactivity
Human, Mouse (Murine)
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128
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2
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Host
Rabbit
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Clonality
Polyclonal
Conjugate
This RPS6KB2 antibody is un-conjugated
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Application
ELISA, Western Blotting (WB)
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107
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27
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5
2
1
Options
Supplier
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Immunogen The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase beta around the phosphorylation site of Ser423.
Isotype IgG
Specificity

p70 S6 Kinase beta (Phospho-Ser423) Antibody detects endogenous levels of p70 S6 Kinase beta only when phosphorylated at Ser423.

PhosphorylationH:S423 M:S423

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Plasmids, Primers & others Plasmids, Primers & others RPS6KB2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name p70 S6 Kinase beta (RPS6KB2 Antibody Abstract)
Background

Synonyms: S6K2, 70 kDa ribosomal protein S6 kinase 2, p70-S6KB, p70 ribosomal S6 kinase beta, p70 S6Kbeta, p70 S6 kinase beta, S6K-beta, p70-beta, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14 beta

NCBI Gene Symbol: RPS6KB2

Molecular Weight 53 kDa
Gene ID 6199
OMIM 608939
UniProt Q9UBS0
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000 ELISA: 1:1000
Comment

Unigene-Number: Hs.534345 (NCBI Gene Symbol: RPS6KB2)

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2) (AA 389-438), (pSer423) antibody (ABIN482681) Western blot analysis of extracts from K562 cells treated with EGF 200ng/ml 5', using...
Background publications Lee-Fruman, Kuo, Lippincott, Terada, Blenis: "Characterization of S6K2, a novel kinase homologous to S6K1." in: Oncogene, Vol. 18, Issue 36, pp. 5108-14, 1999 (PubMed).

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