KCNJ1 antibody (AA 245-259)

Catalog No. ABIN490492

Product Details anti-KCNJ1 Antibody

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Binding Specificity: AA 245-259

Reactivity: Human, Cow, Horse, Monkey, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This KCNJ1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: Human KCNJ1 / Kir1.1. This antibody is expected to recognize reported isoforms NP_722449.2 and NP_000211. The following reported variants represent identical protein: NP_722451.1, NP_722449.2, NP_722450.1, NP_722448.1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Dolphin, Panda, Bovine, Horse, Pig, Opossum, Platypus (100%) Gibbon, Mouse, Rat, Hamster, Elephant, Dog, Rabbit (93%) Bat (87%) Turkey, Chicken (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-DQININFVVDAGNEN from an internal region of human KCNJ1 / Kir1.1 (NP_000211.1, NP_722448.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Dolphin, Panda, Bovine, Horse, Pig, Opossum, Platypus (100%), Gibbon, Mouse, Rat, Hamster, Elephant, Dog, Rabbit (93%), Bat (87%), Turkey, Chicken (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx. 45  kDa band observed in Human, Mouse and Rat Kidney lysates (calculated MW of 44.8  kDa according to NP_000211.1). Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for KCNJ1

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Alternative Name: KCNJ1 / ROMK (KCNJ1 Products)

Synonyms: KIR1.1 antibody, ROMK antibody, ROMK1 antibody, kir1.1 antibody, romk1 antibody, Kcnj antibody, Kir1.1 antibody, Romk2 antibody, kcnj1 antibody, wu:fl37c05 antibody, zgc:63534 antibody, potassium voltage-gated channel subfamily J member 1 antibody, potassium voltage-gated channel subfamily J member 1 L homeolog antibody, potassium inwardly-rectifying channel, subfamily J, member 1 antibody, potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 antibody, KCNJ1 antibody, kcnj1.L antibody, kcnj1 antibody, Kcnj1 antibody, kcnj1a.1 antibody

Background: Name/Gene ID: KCNJ1
Subfamily: Potassium channel - inward-rectifying
Family: Ion channel

Synonyms: KCNJ1, KIR1.1, ROMK1, ROMK3, ROMK5, Inwardly rectifying K+ channel, ROMK, Romk2, ROMK4

Gene ID: 3758

NCBI Accession: NP_000211, NP_722448

UniProt: P48048