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TNFRSF13C antibody (AA 1-30)
TNFRSF13C
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNFRSF13C Antibody
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Target
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TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Binding Specificity
All epitopes for TNFRSF13C antibodies
AA 1-30
Reactivity
All reactivities for TNFRSF13C antibodies
Human
Host
All hosts for TNFRSF13C antibodies
Rabbit
Clonality
All clonalities for TNFRSF13C antibodies
Polyclonal
Conjugate
All conjugates for TNFRSF13C antibodies
This TNFRSF13C antibody is un-conjugated
Application
All applications for TNFRSF13C antibodies
Western Blotting (WB), ELISA
Purification
Antigen affinity purified
Immunogen
A portion of amino acids 1-30 from the human protein was used as the immunogen for this BAFF Receptor antibody.
Isotype
Ig Fraction
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Discover our top product TNFRSF13C Primary Antibody
Alternatives
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Application Details
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Application Notes
Titration of the BAFF Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the BAFF Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for TNFRSF13C
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Target
TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Alternative Name
BAFF Receptor (TNFRSF13C Products )
Synonyms
RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody
Background
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
UniProt
Q96RJ3
Pathways
NF-kappaB Signaling
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