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NFKB1 antibody (AA 1-200)
NFKB1
Reactivity: Human
WB
Host: Mouse
Monoclonal
ABM20H5
unconjugated
Product Details anti-NFKB1 Antibody
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Target
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NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Binding Specificity
All epitopes for NFKB1 antibodies
AA 1-200
Reactivity
All reactivities for NFKB1 antibodies
Human
Host
All hosts for NFKB1 antibodies
Mouse
Clonality
All clonalities for NFKB1 antibodies
Monoclonal
Conjugate
All conjugates for NFKB1 antibodies
This NFKB1 antibody is un-conjugated
Application
All applications for NFKB1 antibodies
Western Blotting (WB)
Purification
Protein G Chromatography
Immunogen
A partial length recombinant p50 protein (amino acids 1-200) was used as the immunogen for this antibody.
Clone
ABM20H5
Isotype
IgG1 kappa
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Discover our top product NFKB1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1-2 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for NFKB1
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Target
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Alternative Name
p105/p50 (NFKB1 Products )
Synonyms
GKLP antibody, NKTL antibody, NTKL antibody, P105 antibody, TAPK antibody, TEIF antibody, TRAP antibody, EBP-1 antibody, KBF1 antibody, NF-kB1 antibody, NF-kappa-B antibody, NF-kappaB antibody, NFKB-p105 antibody, NFKB-p50 antibody, NFkappaB antibody, p105 antibody, p50 antibody, NF-kB antibody, NF-KB1 antibody, ebp-1 antibody, kbf1 antibody, nf-kappa-b antibody, nf-kappaB antibody, nfkb-p105 antibody, nfkb-p50 antibody, NF-kappaB1 antibody, p50/p105 antibody, BICDR-1 antibody, bicdr1 antibody, ccdc64 antibody, SCY1 like pseudokinase 1 antibody, nuclear factor kappa B subunit 1 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antibody, nuclear factor NF-kappa-B p105 subunit antibody, nucleoporin 107 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody, SCYL1 antibody, NFKB1 antibody, Nfkb1 antibody, nfkb1.L antibody, CpipJ_CPIJ012236 antibody, Nup107 antibody, nfkb1 antibody
Background
P50 (KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B) family of transcription factors plays important roles in various biological processes including apoptosis, stress response, immunity, and inflammation. Activation of p50 regulates the expression of inflammatory genes crucially involved in the pathogenesis of inflammatory diseases. It governs the expression of adhesion molecules that play a pivotal role in leukocyte-endothelium interactions. p50 activation plays an essential role in the activation of mesangial cells and macrophages through the transcriptional induction of inflammatory mediators of glomerular inflammation and injury.
Molecular Weight
55.11
Gene ID
4790
UniProt
P19838
Pathways
p53 Signaling , NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , S100 Proteins
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