Raptor antibody (pSer863)

Catalog No. ABIN542672

Product Details anti-Raptor Antibody

Target: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Binding Specificity: pSer863

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Raptor antibody is un-conjugated

Application: Dot Blot (DB)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of RPTOR.

Cross-Reactivity: Human

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S863 of human RPTOR.

Application Details

Application Notes: Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Raptor antibody (ABIN542672)

Fuchs, Finger, Onan, Bode: "ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells." in: American journal of physiology. Cell physiology, Vol. 293, Issue 1, pp. C55-63, (2007) (PubMed).

Wang, Bai, Qin, Zhang, Yi, Teesdale, Zhao, Pober, Tellides: "Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation." in: Circulation research, Vol. 101, Issue 6, pp. 560-9, (2007) (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).

Target Details for Raptor

Target: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Alternative Name: RPTOR (RPTOR Products)

Synonyms: KOG1 antibody, Mip1 antibody, 4932417H02Rik antibody, Rap antibody, Raptor antibody, mKIAA1303 antibody, RGD1311784 antibody, raptor antibody, regulatory associated protein of MTOR complex 1 antibody, regulatory associated protein of MTOR, complex 1 antibody, regulatory associated protein of MTOR, complex 1 L homeolog antibody, RPTOR antibody, Rptor antibody, rptor.L antibody, rptor antibody

Gene ID: 57521

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Autophagy, BCR Signaling, Warburg Effect