Metabotropic Glutamate Receptor 5 antibody (C-Term)

Catalog No. ABIN542969

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of GRM5.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus residues surrounding T1003 of human GRM5.

Application Details

Application Notes: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Metabotropic Glutamate Receptor 5 antibody (ABIN542969)

Pacheco, Ciruela, Casadó, Mallol, Gallart, Lluis, Franco: "Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation." in: The Journal of biological chemistry, Vol. 279, Issue 32, pp. 33352-8, (2004) (PubMed).

Uchino, Sakai, Kashiwagi, Shirai, Shinohara, Hirose, Iino, Yamamura, Saito: "Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 2254-61, (2004) (PubMed).

Anneser, Ince, Shaw, Borasio: "Differential expression of mGluR5 in human lumbosacral motoneurons." in: Neuroreport, Vol. 15, Issue 2, pp. 271-3, (2004) (PubMed).

Target Details for Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Alternative Name: MGluR5 / GRM5 (GRM5 Products)

Synonyms: GPRC1E antibody, MGLUR5 antibody, mGlu5 antibody, mGluR5 antibody, mGlur5 antibody, 6430542K11Rik antibody, AI850523 antibody, Glu5R antibody, Gprc1e antibody, mGluR5b antibody, glutamate receptor, metabotropic 5 antibody, glutamate metabotropic receptor 5 antibody, GRM5 antibody, Grm5 antibody

Gene ID: 2915

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity