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eIF4EBP1 antibody (C-Term)
EIF4EBP1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-eIF4EBP1 Antibody
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Target
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eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Binding Specificity
All epitopes for eIF4EBP1 antibodies
C-Term
Reactivity
All reactivities for eIF4EBP1 antibodies
Human
Host
All hosts for eIF4EBP1 antibodies
Rabbit
Clonality
All clonalities for eIF4EBP1 antibodies
Polyclonal
Conjugate
All conjugates for eIF4EBP1 antibodies
This eIF4EBP1 antibody is un-conjugated
Application
All applications for eIF4EBP1 antibodies
Western Blotting (WB)
Sequence
NSPVTKTPPR DLPTIPGVTS PSSDEPPMEA SQSHLRNSPE DKRAGGEESQ
Characteristics
This is a rabbit polyclonal antibody against 4EBP1. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human 4EBP1
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for eIF4EBP1
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Target
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Alternative Name
4EBP1 (EIF4EBP1 Products )
Synonyms
4E-BP1 antibody, 4EBP1 antibody, BP-1 antibody, PHAS-I antibody, 4e-bp1 antibody, AA959816 antibody, 153432_at antibody, 43-BP antibody, 4E-BP antibody, 4EBP antibody, 4e-bp antibody, 4eBP antibody, 4ebp antibody, BcDNA.HL08053 antibody, BcDNA:HL08053 antibody, CG8846 antibody, CT8705 antibody, Dm 4E-BP antibody, Dmel\\CG8846 antibody, Phas1 antibody, Thor/EIF4EBP antibody, anon-WO0172774.158 antibody, d4E-BP antibody, d4E-BP1 antibody, d4EBP antibody, d4e-bp antibody, d4eBP antibody, dthor antibody, eIF4E-BP antibody, l(2)06270 antibody, l(2)k07736 antibody, l(2)k13517 antibody, pp20 antibody, thor antibody, EIF4EBP1 antibody, fc04h09 antibody, wu:fc04h09 antibody, zgc:64137 antibody, eukaryotic translation initiation factor 4E binding protein 1 antibody, CG8846 gene product from transcript CG8846-RA antibody, EIF4EBP1 antibody, Eif4ebp1 antibody, Thor antibody, eif4ebp1 antibody
Background
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. Alias Symbols: EIF4EBP1, Protein Interaction Partner: Mtor, MLST8, RPTOR, TCF4, REL, EIF4E, RICTOR, MAPKAP1, UBC, SLMAP, LATS1, PRKDC, ATM, PPP2R4, STK3, MAPK14, LRRK2, AGO2, MAPK1, KLHL25, IRAK4, PRKCA, GSK3B, CHTF8, RHEBL1, RPS6KB1, MAPKAPK5, PPP2CA, RPS6KA5, EIF4E2, MVD, RORC, BUB1, AKT1, CSNK2A2, CSNK2A1 Protein Size: 118
Gene ID
1978
NCBI Accession
NP_004086
UniProt
Q13541
Pathways
MAPK Signaling , PI3K-Akt Signaling , RTK Signaling , AMPK Signaling , Regulation of Cell Size , BCR Signaling
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