PUMA antibody (AA 2-16)

Catalog No. ABIN5648821

Product Details anti-PUMA Antibody

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Binding Specificity: AA 2-16

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUMA antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of BBC3.

Specificity: This antibody recognizes an epitope at the N-terminus of human and mouse PUMA (p53 Upregulated Modulator of Apoptosis). PUMA is a pro-apoptotic Bcl-2 family member that encodes two BH3 domain-containing proteins, PUMA-alpha and PUMA-beta.

Cross-Reactivity: Human, Mouse

Cross-Reactivity (Details): This antibody recognizes an epitope at the N-terminus of human and mouse PUMA (p53 Upregulated Modulator of Apoptosis). PUMA is a pro-apoptotic Bcl-2 family member that encodes two BH3 domain-containing proteins, PUMA-alpha and PUMA-beta.

Immunogen: A synthetic peptide corresponding to amino acids 2-16 of human BBC3.

Application Details

Application Notes: Western Blot (2-4 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Target Details for PUMA

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Alternative Name: BBC3 (BBC3 Products)

Synonyms: BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody

Background: Full Gene Name: BCL2 binding component 3
Synonyms: JFY1,PUMA

Gene ID: 27113

Pathways: p53 Signaling, Positive Regulation of Endopeptidase Activity