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JAK1 antibody (pTyr1022)
JAK1
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-JAK1 Antibody
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Target
See all JAK1 Antibodies
JAK1
(Janus Kinase 1 (JAK1))
Binding Specificity
All epitopes for JAK1 antibodies
pTyr1022
Reactivity
All reactivities for JAK1 antibodies
Human, Mouse, Rat
Host
All hosts for JAK1 antibodies
Rabbit
Clonality
All clonalities for JAK1 antibodies
Polyclonal
Conjugate
All conjugates for JAK1 antibodies
This JAK1 antibody is un-conjugated
Application
All applications for JAK1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
This antibody detects endogenous level of JAK1 only when phosphorylated at tyrosine 1022.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Immunogen
JAK1 (Phospho-Tyr1022) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1022 (K-E-Y (p) -Y-T) derived from Human JAK1.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for JAK1
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Target
JAK1
(Janus Kinase 1 (JAK1))
Alternative Name
JAK1 (JAK1 Products )
Synonyms
JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
Background
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
Molecular Weight
130 kDa
Gene ID
3716
NCBI Accession
NP_002218
UniProt
P23458
Pathways
JAK-STAT Signaling , RTK Signaling , Interferon-gamma Pathway , Hepatitis C , Toll-Like Receptors Cascades , Unfolded Protein Response
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