Caspase 4 antibody
-
- Target See all Caspase 4 (CASP4) Antibodies
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Caspase 4 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of mouse CASP4
- Isotype
- IgG
- Top Product
- Discover our top product CASP4 Primary Antibody
-
-
- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
- Alternative Name
- CASP4 (CASP4 Products)
- Synonyms
- ICE(rel)II antibody, ICEREL-II antibody, ICH-2 antibody, Mih1/TX antibody, TX antibody, Casp11 antibody, CASP13 antibody, CASP1 antibody, CASP4 antibody, Caspl antibody, ich-3 antibody, Casp4 antibody, caspase 4 antibody, caspase 4, apoptosis-related cysteine peptidase antibody, caspase-4 antibody, CASP4 antibody, Casp4 antibody, LOC100731032 antibody
- Background
-
Synonyms: Apoptotic cysteine protease Mih1/TX,CASP-4,CASP4,CASP4,Caspase 4 apoptosis related cysteine peptidase,Caspase-4 subunit 2,Caspase4,ICE(rel)-II,ICE(rel)II,ICEREL II,ICH2,Mih1/TX,Protease ICH-2,Protease TX,TX
Background: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
- Molecular Weight
-
Observed_MW: 43-48kDa
Calculated_MW: 13kDa/18kDa/30kDa/36kDa/43kDa
- Gene ID
- 12363
- UniProt
- P70343
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
-