EIF2AK2 antibody
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- Target See all EIF2AK2 Antibodies
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EIF2AK2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human Eif2ak2
- Isotype
- IgG
- Top Product
- Discover our top product EIF2AK2 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IHC 1:100 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Alternative Name
- EIF2AK2 (EIF2AK2 Products)
- Synonyms
- PKR antibody, pkr antibody, EIF2AK2 antibody, DKFZp469K1934 antibody, EIF2AK1 antibody, PRKR antibody, 2310047A08Rik antibody, 4732414G15Rik antibody, AI467567 antibody, AI747578 antibody, Pkr antibody, Prkr antibody, Tik antibody, eukaryotic translation initiation factor 2 alpha kinase 2 antibody, eukaryotic translation initiation factor 2-alpha kinase 2 antibody, EIF2AK2 antibody, eif2ak2 antibody, Eif2ak2 antibody
- Background
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Synonyms: Double stranded RNA activated protein kinase,E2AK2,eIF-2A protein kinase 2,EIF2AK1,EIF2AK2,Eukaryotic translation initiation factor 2 alpha kinase 2,Eukaryotic translation initiation factor 2-alpha kinase 2,HGNC:9437,Interferon induced double stranded RNA activated protein kinase,Interferon inducible elF2 alpha kinase,Interferon inducible RNA dependent protein kinase,Interferon-induced,double-stranded RNA-activated protein kinase,Interferon-inducible RNA-dependent protein kinase,MGC126524,P1/eIF-2A protein kinase,P1/eIF2A protein kinase,p68 kinase,PKR,PPP1R83,PRKR,Protein kinase interferon inducible double stranded RNA dependent,Protein kinase RNA activated,Protein kinase RNA-activated,Protein phosphatase 1 regulatory subunit 83,Serine/threonine protein kinase TIK,Tyrosine protein kinase EIF2AK2
Background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 73kDa, 80kDa
Calculated_MW: 57kDa/62kDa
- Gene ID
- 5610
- UniProt
- P19525
- Pathways
- DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C
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