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GZMB antibody

GZMB Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6241151
  • Target See all GZMB Antibodies
    GZMB (Granzyme B (GZMB))
    Reactivity
    • 117
    • 48
    • 23
    • 10
    • 4
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 77
    • 43
    • 1
    Rabbit
    Clonality
    • 75
    • 46
    Polyclonal
    Conjugate
    • 75
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is un-conjugated
    Application
    • 70
    • 41
    • 37
    • 37
    • 17
    • 17
    • 17
    • 14
    • 13
    • 9
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Immunogen
    Synthetic Peptide
    Top Product
    Discover our top product GZMB Primary Antibody
  • Application Notes
    WB: 1:1000. IHC: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C,-20 °C
  • Target
    GZMB (Granzyme B (GZMB))
    Alternative Name
    Granzyme B (GZMB Products)
    Synonyms
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    Background
    This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
    UniProt
    P10144
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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