GZMB antibody
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- Target See all GZMB Antibodies
- GZMB (Granzyme B (GZMB))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GZMB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Immunogen
- Synthetic Peptide
- Top Product
- Discover our top product GZMB Primary Antibody
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- Application Notes
- WB: 1:1000. IHC: 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- 4 °C,-20 °C
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- Granzyme B (GZMB Products)
- Synonyms
- CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
- Background
- This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
- UniProt
- P10144
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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