TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b)

Details for Product anti-TNFRSF10B Antibody No. ABIN6265635
Antigen
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Alternatives
anti-Human TNFRSF10B antibody for Flow Cytometry
Reactivity
Human
289
61
30
1
1
1
1
1
Host
Rabbit
186
131
6
2
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
18
15
12
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
1
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
178
102
73
56
42
30
29
27
13
13
12
8
3
3
2
1
Options
Immunogen A synthesized peptide derived from human TNFRSF10B
Isotype IgG
Specificity TNFRSF10B Antibody detects endogenous levels of total TNFRSF10B
Cross-Reactivity Human
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Plasmids, Primers & others Plasmids, Primers & others TNFRSF10B products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TNFRSF10B (TNFRSF10B Antibody Abstract)
Background

Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

Gene: TNFRSF10B

Molecular Weight 48kDa
Gene ID 8795
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
Application Notes WB 1:500-1:2000 IHC 1:50-1:200
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibody (ABIN6265635) Western blot analysis of HL-60 lysate using TNFRSF10B antibody. The lane on the left...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibody (ABIN6265635) ABIN6276636 at 1/100 staining Human prostate tissue by IHC-P. The sample was formalde...
Product cited in: Luo, Pan, Liu, Yuan, Yan: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, 2018 (PubMed).

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