FANCD2 antibody (pSer222)

Catalog No. ABIN6281618

Product Details anti-FANCD2 Antibody

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Binding Specificity: AA 160-240, pSer222

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal to Phospho-FANCD2 (S222).

Specificity: Phospho-FANCD2 (S222) Polyclonal Antibody detects endogenous levels of FANCD2 protein only when phosphorylated at S222.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FANCD2 around the phosphorylation site of S222.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

Comment:

Highly expressed in germinal center cells of the spleen, tonsil, and reactive lymph nodes, and in the proliferating basal layer of squamous epithelium of tonsil, esophagus, oropharynx, larynx and cervix. Expressed in cytotrophoblastic cells of the placenta and exocrine cells of the pancreas (at protein level). Highly expressed in testis, where expression is restricted to maturing spermatocytes.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for FANCD2

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Alternative Name: FANCD2 (FANCD2 Products)

Synonyms: FANCD2 antibody, CG17269 antibody, CG31192 antibody, CG31194 antibody, Dmel\\CG17269 antibody, dmFANCD2 antibody, xfancd2 antibody, FA-D2 antibody, FA4 antibody, FACD antibody, FAD antibody, FAD2 antibody, FANCD antibody, 2410150O07Rik antibody, AU015151 antibody, BB137857 antibody, Fanconi anemia complementation group D2 antibody, CG17269 gene product from transcript CG17269-RA antibody, Fanconi anemia group D2 protein antibody, Fanconi anemia, complementation group D2 antibody, Fanconi anemia complementation group D2 L homeolog antibody, FANCD2 antibody, Fancd2 antibody, LOC100455970 antibody, fancd2 antibody, fancd2.L antibody

Molecular Weight: 166 kDa

Gene ID: 2177

UniProt: Q9BXW9

Pathways: DNA Damage Repair