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Metabotropic Glutamate Receptor 5 antibody
GRM5
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Metabotropic Glutamate Receptor 5 Antibody
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Target
See all Metabotropic Glutamate Receptor 5 (GRM5) Antibodies
Metabotropic Glutamate Receptor 5 (GRM5)
(Glutamate Receptor, Metabotropic 5 (GRM5))
Reactivity
All reactivities for Metabotropic Glutamate Receptor 5 antibodies
Human
Host
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Rabbit
Clonality
All clonalities for Metabotropic Glutamate Receptor 5 antibodies
Polyclonal
Conjugate
All conjugates for Metabotropic Glutamate Receptor 5 antibodies
This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
Application
All applications for Metabotropic Glutamate Receptor 5 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Affinity chromatography purified
Immunogen
GRM5 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Discover our top product GRM5 Primary Antibody
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Application Details
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Application Notes
IHC-P: 5.6 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target Details for Metabotropic Glutamate Receptor 5
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Target
Metabotropic Glutamate Receptor 5 (GRM5)
(Glutamate Receptor, Metabotropic 5 (GRM5))
Alternative Name
GRM5 (GRM5 Products )
Synonyms
GPRC1E antibody, MGLUR5 antibody, mGlu5 antibody, mGluR5 antibody, mGlur5 antibody, 6430542K11Rik antibody, AI850523 antibody, Glu5R antibody, Gprc1e antibody, mGluR5b antibody, glutamate receptor, metabotropic 5 antibody, glutamate metabotropic receptor 5 antibody, GRM5 antibody, Grm5 antibody
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C.
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling , Regulation of long-term Neuronal Synaptic Plasticity
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