RASSF1 antibody
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- Target See all RASSF1 Antibodies
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RASSF1 antibody is un-conjugated
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Application
- Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human RASSF1 (NP_009113.3).
- Isotype
- IgG
- Top Product
- Discover our top product RASSF1 Primary Antibody
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- Application Notes
- IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Alternative Name
- RASSF1 (RASSF1 Products)
- Synonyms
- RASSF1 antibody, zgc:92505 antibody, wu:fc17f02 antibody, zgc:112224 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, AA536941 antibody, AU044980 antibody, Rassf1A antibody, Rassf1B antibody, Rassf1C antibody, NPR2-like, GATOR1 complex subunit antibody, Ras association (RalGDS/AF-6) domain family 1 antibody, Ras association domain family member 1 antibody, putative rassf1 antibody, Ras association domain family member 1 L homeolog antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, NPRL2 antibody, rassf1 antibody, RASSF1 antibody, Smp_157340 antibody, rassf1.L antibody, Rassf1 antibody
- Background
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Molecular Weight
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Observed_MW: 39kDa
Calculated_MW: 8kDa/9kDa/16kDa/21kDa/31kDa/38kDa/39kDa
- Gene ID
- 11186
- UniProt
- Q9NS23
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