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NLRP12 antibody
NLRP12
Reactivity: Mouse
WB
Host: Mouse
Monoclonal
228CT4-1-3
unconjugated
Product Details anti-NLRP12 Antibody
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Target
See all NLRP12 Antibodies
NLRP12
(NLR Family, Pyrin Domain Containing 12 (NLRP12))
Reactivity
All reactivities for NLRP12 antibodies
Mouse
Host
All hosts for NLRP12 antibodies
Mouse
Clonality
All clonalities for NLRP12 antibodies
Monoclonal
Conjugate
All conjugates for NLRP12 antibodies
This NLRP12 antibody is un-conjugated
Application
All applications for NLRP12 antibodies
Western Blotting (WB)
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.
Clone
228CT4-1-3
Isotype
IgM kappa
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Alternatives
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Application Details
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Application Notes
WB: 1:500~1500
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for NLRP12
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Target
NLRP12
(NLR Family, Pyrin Domain Containing 12 (NLRP12))
Alternative Name
NLRP12 (NLRP12 Products )
Synonyms
Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody
Background
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
Molecular Weight
120173
Gene ID
91662
NCBI Accession
NP_001264055 , NP_001264058 , NP_653288
UniProt
P59046
Pathways
Positive Regulation of Endopeptidase Activity , Inflammasome
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