NLRP12 antibody

Catalog No. ABIN659108

Product Details anti-NLRP12 Antibody

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NLRP12 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.

Clone: 228CT4-1-3

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:500~1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Alternative Name: NLRP12 (NLRP12 Products)

Synonyms: Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody

Background: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

Molecular Weight: 120173

Gene ID: 91662

NCBI Accession: NP_001264055, NP_001264058, NP_653288

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome