CD45RA antibody (APC)

Catalog No. ABIN6731167

Product Details anti-CD45RA Antibody (APC)

Target: CD45RA

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD45RA antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Characteristics: The clone OTH-74D4 recognizes a 220 kD isoform of the leucocyte common antigen (LCA) of the CD45 antigen family. The CD45RA antigen is expressed mostly on naive CD4+, CD8+ and gd+ T and on most B and NK lymphocytes. Generally the CD45RA antigen density decreases upon activation. The CD45RA expression on immune cells is used as one of the key surface antigen to determine the functional status and also to define the end-stage of human T cells.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: An EBV-transformed B cell line from a patient with MHC class II deficiency

Clone: OTH-74D4

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD45RA

Target: CD45RA

Alternative Name: CD45RA (CD45RA Products)

Synonyms: B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Lca antibody, RT7 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, PTPRC antibody, Ptprc antibody

Background: The clone OTH-74D4 recognizes a 220 kD isoform of the leucocyte common antigen (LCA) of the CD45 antigen family. The CD45RA antigen is expressed mostly on naive CD4+, CD8+ and gd+ T and on most B and NK lymphocytes. Generally the CD45RA antigen density decreases upon activation. The CD45RA expression on immune cells is used as one of the key surface antigen to determine the functional status and also to define the end-stage of human T cells.

Gene ID: 5788

NCBI Accession: NM_002838

UniProt: P08575