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BAX antibody

BAX Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Mouse Monoclonal 1D8 unconjugated
Catalog No. ABIN7250314
  • Target See all BAX Antibodies
    BAX (BCL2-Associated X Protein (BAX))
    Reactivity
    • 257
    • 157
    • 141
    • 47
    • 32
    • 26
    • 25
    • 18
    • 16
    • 12
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 171
    • 94
    • 3
    • 1
    Mouse
    Clonality
    • 185
    • 84
    Monoclonal
    Conjugate
    • 135
    • 16
    • 13
    • 12
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAX antibody is un-conjugated
    Application
    • 235
    • 114
    • 73
    • 63
    • 52
    • 52
    • 50
    • 40
    • 36
    • 13
    • 12
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Characteristics
    Monoclonal Antibody
    Purification
    Protein A purification
    Immunogen
    Synthetic Peptide of Bax
    Clone
    1D8
    Isotype
    IgG
    Top Product
    Discover our top product BAX Primary Antibody
  • Application Notes
    WB 1:1000-2000, IHC 1:100-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BAX (BCL2-Associated X Protein (BAX))
    Alternative Name
    BAX (BAX Products)
    Synonyms
    BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody
    Background
    Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
    Molecular Weight
    20 kDa
    UniProt
    Q07812
    Pathways
    p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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