APH1A antibody (AA 90-118) (HRP)
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- Target See all APH1A Antibodies
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
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Binding Specificity
- AA 90-118
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APH1A antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Gamma-secretase subunit APH-1A protein (90-118AA)
- Isotype
- IgG
- Top Product
- Discover our top product APH1A Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
- Alternative Name
- APH1A (APH1A Products)
- Synonyms
- 6530402N02Rik antibody, APH-1 antibody, APH-1A antibody, CGI-78 antibody, RGD1311546 antibody, APH-1a antibody, aph-1 homolog A, gamma-secretase subunit antibody, aph-1 homolog A, gamma secretase subunit L homeolog antibody, aph-1 homolog A, gamma secretase subunit antibody, anterior pharynx defective 1 homolog A (C. elegans) antibody, aph1 homolog A, gamma secretase subunit antibody, acylamino-acid-releasing enzyme-like antibody, APH1A antibody, aph1a.L antibody, Aph1a antibody, LOC100219182 antibody
- Background
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Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Aliases: 6530402N02Rik antibody, AL138795.3 antibody, Anterior Pharynx Defective 1 antibody, Anterior pharynx defective 1 homolog A antibody, APH 1A antibody, Aph 1alpha antibody, APH-1a antibody, Aph-1alpha antibody, Aph1a antibody, APH1A gamma secretase subunit antibody, APH1A_HUMAN antibody, CGI 78 antibody, CGI78 antibody, Gamma secretase subunit APH 1A antibody, Gamma Secretase Subunit APH1a antibody, Gamma-secretase subunit APH-1A antibody, Likely ortholog of C. elegans anterior pharynx defective 1A antibody, Presenilin Stabilization Factor antibody, Presenilin-stabilization factor antibody, PSF antibody, UNQ579/PRO1141 antibody
- UniProt
- Q96BI3
- Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
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