STAT5B antibody (N-Term)
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- Target See all STAT5B Antibodies
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish (Danio rerio), Chicken, Xenopus laevis
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STAT5B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus), Chicken, Pig (Porcine), Cow (Bovine), Dog (Canine), Zebrafish (Brachydanio rerio), Frog
- Purification
- Purified
- Immunogen
- STAT5 B antibody was raised in rabbit using the N terminal of STAT5 as the immunogen
- Top Product
- Discover our top product STAT5B Primary Antibody
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- Application Notes
- Optimal conditions should be determined by the investigator.
- Comment
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STAT5B Blocking Peptide, catalog no. 33R-1622, is also available for use as a blocking control in assays to test for specificity of this STAT5B antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
- Alternative Name
- STAT5B (STAT5B Products)
- Synonyms
- STAT5 antibody, stat5 antibody, STAT5A antibody, STAT5B antibody, signal transducer and activator of transcription 5B antibody, signal transducer and activator of transcription 5B S homeolog antibody, Signal transducer and activator of transcription 5B antibody, STAT5B antibody, Stat5b antibody, stat5b.S antibody, LOC490969 antibody, sta5b antibody, LOC100566752 antibody, LOC100052954 antibody
- Background
- The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Synonyms: Polyclonal STAT5B antibody, Anti-STAT5B antibody, signal transducer and activator of transcription 5B antibody, STAT5 antibody.
- Pathways
- JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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