Epigenetics is defined as the stable and heritable alternations in gene expression without changing the DNA nucleotide sequence. The initiation and progression of cancer result from not only genetic mutation, but also aberrant epigenetic regulation, such as DNA methylation and histones acetylation. Although genetic alternations cannot be reversed, epigenetic modification is a dynamic and reversible process.
Over the past few decades, much progress has been made in the research of epigenetic medications and a variety of drugs have been developed targeting epigenetic regulatory proteins, which are capable of restoring malignant cancer cells to the normal state. The epigenetic drugs currently approved for cancer treatment mainly target at DNA methylation and histones acetylation. In addition, there are a great many epigenetic drugs in clinical trials for cancer therapy. antibodies-online.com is able to support your research on epigenetic drugs.
antibodies-online.com offers inhibitors of important epigentic targets such as inhibitors of DNA methyltransferases, histone deacetylases, histone methyltransferases, lysine specific demethylases, and BET (bromodomain and extra-terminal domain) family proteins. Discover our selection down below or browse all available inhibitors.
Epigenetic Inhibitors against:
Acetyltransferase Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
HAT Inhibitor
Cat. No.
ABIN7233231
Principle
XIAP inhibitor, Apoptosis inducer
Cat. No.
ABIN7233250
Principle
p300 HAT activator
Cat. No.
ABIN7233245
Principle
Acetyl-transferase NAT10 inhibitor
Cat. No.
ABIN7233278
Principle
HAT inhibitor
Cat. No.
ABIN7233244
Principle
HAT inhibitor
Cat. No.
ABIN7233254
Principle
HAT inhibitor
Cat. No.
ABIN7233239
Bromodomain Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
Bromodomain inhibitor
Cat. No.
ABIN7233275
Principle
Bromodomain inhibitor
Cat. No.
ABIN7233265
Principle
BET bromodomain inhibitor
Cat. No.
ABIN7233283
Principle
Dual Plk/BRD4 inhibitor, Destabilizes Myc
Cat. No.
ABIN7233234
Principle
BET Bromodomain inhibitor, Suppresses Myc transcription
Cat. No.
ABIN7233261
Principle
Pan-bromodomain inhibitor
Cat. No.
ABIN7233238
Principle
Bromodomain inhibitor
Cat. No.
ABIN7233264
DNA Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
Methyl-lysine binding protein inhibitor
Cat. No.
ABIN7233306
DNA Methyltransferase Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
DNA hypomethylation agent
Cat. No.
ABIN7233228
Principle
Transcription inhibitor, Inhibits DNA methyltransferase
Cat. No.
ABIN7233267
Principle
DNA methyltransferase inhibitor
Cat. No.
ABIN7233280
Principle
MGMT inhibitor
Cat. No.
ABIN7233266
Principle
DNA methylation inhibitor
Cat. No.
ABIN7233307
Principle
DNA hypomethylation agent
Cat. No.
ABIN7233248
Principle
DNA methyltransferase inhibitor
Cat. No.
ABIN7233289
Principle
Methyl-lysine binding protein inhibitor
Cat. No.
ABIN7233306
Kinase Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
Dual HDAC and EGFR inhibitor
Cat. No.
ABIN7233246
Protein Deacetylase Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
SIRT1 inhibitor, essential nutrient
Cat. No.
ABIN7233271
Principle
HDAC inhibitor
Cat. No.
ABIN7233284
Principle
HDAC inhibitor
Cat. No.
ABIN7233276
Principle
SIRT1 and 2 inhibitor
Cat. No.
ABIN7233298
Principle
HDAC inhibitor
Cat. No.
ABIN7233292
Principle
Antioxidant, SIRT1 activator
Cat. No.
ABIN7233279
Principle
HDAC inhibitor
Cat. No.
ABIN7233272
Principle
HDAC inhibitor
Cat. No.
ABIN7233260
Principle
SIRT1 inhibitor
Cat. No.
ABIN7233252
Principle
SIRT1 activator, Tyrosine kinase inhibitor
Cat. No.
ABIN7233277
Principle
Ultrapotent HDAC2 inhibitor
Cat. No.
ABIN7233286
Principle
HDAC8 activator
Cat. No.
ABIN7233299
Principle
SIRT1&2 inhibitor
Cat. No.
ABIN7233285
Principle
HDAC inhibitor
Cat. No.
ABIN7233270
Principle
HDAC6 inhibitor
Cat. No.
ABIN7233303
Principle
SIRT activator, prodrug
Cat. No.
ABIN7233301
Principle
SIRT1 inhibitor
Cat. No.
ABIN7233294
Principle
SIRT inhibitor
Cat. No.
ABIN7233291
Principle
HDAC inhibitor
Cat. No.
ABIN7233282
Principle
Selective HDAC3 inhibitor
Cat. No.
ABIN7233281
Principle
Class I HDAC inhibitor
Cat. No.
ABIN7233269
Principle
SIRT1 activator
Cat. No.
ABIN7233295
Principle
HDAC inhibitor
Cat. No.
ABIN7233287
Principle
HDAC inhibitor
Cat. No.
ABIN7233302
Principle
SIRT1 activator
Cat. No.
ABIN7233290
Protein Demethylase Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
Demethylase inhibitor
Cat. No.
ABIN7233300
Principle
KDM2/7 demethylase inhibitor
Cat. No.
ABIN7233247
Principle
JMJD2 inhibitor
Cat. No.
ABIN7233268
Principle
JMJ H3K27 Demethylase inhibitor (cell permeable)
Cat. No.
ABIN7233259
Principle
pan-JUMONJI histone demethylase inhibitor
Cat. No.
ABIN7233263
Principle
JARID1 inhibitor
Cat. No.
ABIN7233273
Principle
JMJD demethylase inhibitor
Cat. No.
ABIN7233262
Principle
LSD1 Inhibitor
Cat. No.
ABIN7233293
Principle
JMJ H3K27 Demethylase inhibitor (cell impermeable)
Cat. No.
ABIN7233258
Principle
Lysine Demethylase inhibitor
Cat. No.
ABIN7233256
Protein Methyltransferase Inhibitors
Product
Principle
Cat. No.
Datasheet
Principle
Selective PRMT5 inhibitor
Cat. No.
ABIN7233257
Principle
EZH2 inhibitor
Cat. No.
ABIN7233296
Principle
Methyltransferase inhibitor
Cat. No.
ABIN7233305
Principle
Arginine methyl transferase 1 (PRMT1) inhibitor
Cat. No.
ABIN7233297
Principle
SETD8 inhibitor
Cat. No.
ABIN7233304
Principle
PRMT3 inhibitor
Cat. No.
ABIN7233288
Principle
EZH2 Histone methyltransferase inhibitor
Cat. No.
ABIN7233255
Principle
Methyltransferase SETD7 inhibitor
Cat. No.
ABIN7233274
Principle
PRC2 methyltransferase inhibitor
Cat. No.
ABIN7233249
Principle
Potent and selective PRMT5 inhibitor
Cat. No.
ABIN7233251
