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CD51/CD61 Proteins

(ITGAV/ITGB3)
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009].
CD51/CD61 Protein (AA 31-992) (His tag) CD51/CD61 Protein (AA 31-992) (His tag) CD51/CD61 Protein (AA 31-992) (His tag) (ABIN2870663)

ITGAV/ITGB3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

CD51/CD61 Protein (His tag) (ABIN7447982)

MALS verified ITGAV/ITGB3 Origin: Rat Host: HEK-293 Cells Recombinant 95,00 %

CD51/CD61 Proteins by Grade

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CD51/CD61 Proteins by Origin

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CD51/CD61 Proteins by Source

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CD51/CD61 Proteins by Protein Type

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CD51/CD61 Proteins by Biological Activity

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Popular CD51/CD61 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN2870663
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source HEK-293 Cells
Validations
Cat. No. ABIN7447982
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD51/CD61 Proteins

Kondo, Wakamori, Hirata, Temma: "Radioiodinated bicyclic RGD peptide for imaging integrin αvβ3 in cancers." in: Biochemical and biophysical research communications, Vol. 528, Issue 1, pp. 168-173, (2021) (PubMed).

Aliases for CD51/CD61 Proteins

integrin subunit alpha V (ITGAV) Proteins
CD51 Proteins
MSK8 Proteins
VNRA Proteins
VTNR Proteins
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