anti-Human LAT2 antibody for Enzyme Immunoassay

Recommended LAT2 Antibody (supplied by: Log in to see )

Antigen
Linker For Activation of T Cells Family, Member 2 (LAT2) Antibodies
  • LAB
  • NTAL
  • WBSCR15
  • WBSCR5
  • WSCR5
  • LAT2
  • MGC139435
  • Ntal
  • Wbscr5
  • AW125574
  • Wbscr15
  • linker for activation of T-cells family member 2
  • linker for activation of T cells family, member 2
  • LAT2
  • Lat2
Epitope
AA 106-135, Middle Region
16
15
11
11
11
10
8
7
6
5
5
5
5
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
117
36
24
3
3
3
1
1
1
1
1
Host
Rabbit
94
36
14
1
Clonality
Polyclonal
Conjugate
This LAT2 antibody is un-conjugated
8
6
6
3
3
3
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
134
43
32
29
21
16
12
6
5
3
3
1
1
1
Options
Supplier
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Available images

Catalog No. ABIN953143
$ 484.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5540458 EIA WB Goat Internal Region Log in to see Polyclonal 0

General

Antigen Linker For Activation of T Cells Family, Member 2 (LAT2) Antibodies
Epitope AA 106-135, Middle Region
(16), (15), (11), (11), (11), (10), (8), (7), (6), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(117), (36), (24), (3), (3), (3), (1), (1), (1), (1), (1)
Host Rabbit
(94), (36), (14), (1)
Clonality
Polyclonal
Conjugate This LAT2 antibody is un-conjugated
(8), (6), (6), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(134), (43), (32), (29), (21), (16), (12), (6), (5), (3), (3), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-LAT2 Antibody

Target Details LAT2 Application Details Handling References for anti-LAT2 antibody (ABIN953143) Images
Specificity This antibody recognizes LAT2 / WBSCR15.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a Protein A column followed by peptide affinity purification
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 106-135aa) of human LAT2 / WBSCR15.
Isotype Ig Fraction
Plasmids, Primers & others

Target Details LAT2

Product Details anti-LAT2 Antibody Application Details Handling References for anti-LAT2 antibody (ABIN953143) Images back to top
Antigen
Alternative Name LAT2 / WBSCR15 (LAT2 Antibody Abstract)
Background The LAT2 gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.Synonyms: HSPC046, LAB, LLinker for activation of B-cells, Linker for activation of T-cells family member 2, Membrane-associated adapter molecule, NTAL, Non-T-cell activation linker, WBS15, WBSCR5, Williams-Beuren syndrome chromosomal region 15 protein
Gene ID 7462
NCBI Accession NP_054865
Pathways Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-LAT2 Antibody Target Details LAT2 Handling References for anti-LAT2 antibody (ABIN953143) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-LAT2 Antibody Target Details LAT2 Application Details References for anti-LAT2 antibody (ABIN953143) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-LAT2 antibody (ABIN953143)

Product Details anti-LAT2 Antibody Target Details LAT2 Application Details Handling Images back to top
Background publications

Rieke, Kähne, Schweitzer, Schraven, Wienands, Engelke, Naumann: "Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infected epithelial cells." in: Cellular signalling, Vol. 22, Issue 3, pp. 395-403, 2009

Luo, Yin, Reierstad, Ishikawa, Lin, Pavone, Zhao, Marsh, Bulun: "Progesterone and mifepristone regulate L-type amino acid transporter 2 and 4F2 heavy chain expression in uterine leiomyoma cells." in: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4533-9, 2009

Svojgr, Burjanivova, Vaskova, Kalina, Stary, Trka, Zuna: "Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia." in: Immunology letters, Vol. 122, Issue 2, pp. 185-92, 2009

Saito, Kawamoto, Kamatani: "Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects." in: Journal of human genetics, Vol. 54, Issue 6, pp. 317-23, 2009

Whittaker, Burshtyn, Orr, Quigley, Hodge, Pascal, Zhang, McVicar: "Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire." in: Blood, Vol. 112, Issue 7, pp. 2869-77, 2008

Images

Product Details anti-LAT2 Antibody Target Details LAT2 Application Details Handling References for anti-LAT2 antibody (ABIN953143) back to top
Supplier Images
Western Blotting (WB) image for anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 106-135), (Middle Region) antibody (ABIN953143) Western blot analysis in Hela cell line lysates (35ug/lane) using LAT2 / WBSCR15  Ant...