Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HTR2C Products

(5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured HTR2C Categories

HTR2C Antibodies

High quality antibodies with extensive validation data.

HTR2C ELISA Kits

Reliable ELISA kits for a wide range of species.

HTR2C Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HTR2C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (6)
Cat. No. ABIN2792274
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN6257909
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7127314
Quantity 100 μL
Datasheet Datasheet

Recommended HTR2C ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953364
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674799
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674800
Quantity 96 tests
Datasheet Datasheet

Recommended HTR2C Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133797
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088308
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307274
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our HTR2C products

Price, Pavlik, Liu, Ding, Wyatt, Sisson: "Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 312, Issue 3, pp. L432-L439, (2017) (PubMed).

Canal, Felsing, Liu, Zhu, Wood, Perry, Vemula, Booth: "An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist that Corrects Motor Stereotypy in Mouse Models." in: ACS chemical neuroscience, Vol. 6, Issue 7, pp. 1259-70, (2015) (PubMed).

Zhang, Li, Xin, Lao, Ren, Berman, Tan, Zhang: "Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model." in: Neurochemical research, Vol. 36, Issue 10, pp. 1785-92, (2011) (PubMed).

Coulon, Kanyshkova, Broicher, Munsch, Wettschureck, Seidenbecher, Meuth, Offermanns, Pape, Budde: "Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling." in: Frontiers in cellular neuroscience, Vol. 4, pp. 132, (2011) (PubMed).

Yang, Mahaffey, Bérubé, Maddatu, Cox, Frankel: "Complex seizure disorder caused by Brunol4 deficiency in mice." in: PLoS genetics, Vol. 3, Issue 7, pp. e124, (2007) (PubMed).

Castensson, Aberg, McCarthy, Saetre, Andersson, Jazin: "Serotonin receptor 2C (HTR2C) and schizophrenia: examination of possible medication and genetic influences on expression levels." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 134B, Issue 1, pp. 84-9, (2005) (PubMed).

Holmes: "5-Hydroxytryptamine2C receptors on pudendal motoneurons innervating the external anal sphincter." in: Brain research, Vol. 1057, Issue 1-2, pp. 65-71, (2005) (PubMed).

Synonyms and alternative names related to HTR2C

5-hydroxytryptamine receptor 2C (HTR2C), 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c), 5-hydroxytryptamine receptor 2C (Htr2c), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog (htr2c.S), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 (htr2cl1), 5-hydroxytryptamine receptor 2C (LOC407134), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (HTR2C), 5-HT-2C, 5-HT2C, 5-HT2cR, 5-ht2cr, 5-HTR2C, 5HT-1C, 5HT1c, 5HT2C, 5ht2c, 5HTR2C, HTR1C, Htr1c, si:dkey-24g18.2, SR1

Protein level used designations for HTR2C

  • 5-HT-1C
  • 5-HT-2C
  • 5-HT1C
  • 5-hydroxytryptamine receptor 1C
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor-1c
  • serotonin 5-HT-2C receptor
  • serotonin receptor 2C
  • 5-HT2C receptor
  • serotonin 1c receptor
  • 5-hydroxytryptamine (serotonin) receptor 2C
  • 5HT2C serotonin receptor
  • 5-HT2C
  • 5-alpha-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
You are here:
Support