Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL-11 Protein (AA 22-199)

IL11 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Catalog No. ABIN2018052
  • Target See all IL-11 (IL11) Proteins
    IL-11 (IL11) (Interleukin 11 (IL11))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 22-199
    Origin
    • 17
    • 9
    • 2
    • 2
    Human
    Source
    • 12
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    CHO Cells
    Characteristics
    ED50 <5 ng/mL, measured in a proliferation assay using T11 cells.
    Purity
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL11 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant Human Interleukin-11 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Interleukin-11 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
    Expiry Date
    6 months
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Alternative Name
    Interleukin-11 (IL11 Products)
    Synonyms
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    Background
    Interleukin-11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 has multiple effects on both hematopoietic and non-hematopoietic cells. Many of the biological effects described for IL-11 overlap with those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell-dependent development of specific immunoglobulin-secreting B cells.
    Synonyms: AGIF (Adipogenesis inhibitory factor)
    Molecular Weight
    23 kDa, observed by reducing SDS-PAGE.
    UniProt
    P20809
    Pathways
    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
You are here:
Support