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Thymic Stromal Lymphopoietin Protein (TSLP) (AA 29-159) (His tag)

TSLP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN6387542
  • Target See all Thymic Stromal Lymphopoietin (TSLP) Proteins
    Thymic Stromal Lymphopoietin (TSLP)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-159
    Origin
    • 24
    • 10
    • 5
    • 3
    Human
    Source
    • 17
    • 16
    • 4
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Thymic Stromal Lymphopoietin protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSYDFTNCD FEKIKAAYLS TISKDLITYM SGTKSTEFNN TVSCSNRPHC LTEIQSLTFN PTAGCASLAK EMFAMKTKAA LAIWCPGYSE TQINATQAMK KRRKRKVTTN KCLEQVSQLQ GLWRRFNRPL LKQQ
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product TSLP Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % Glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    Thymic Stromal Lymphopoietin (TSLP)
    Alternative Name
    TSLP (TSLP Products)
    Synonyms
    TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
    Background
    TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. TSLP is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. Recombinant human TSLP protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    17.3kDa (154aa)
    NCBI Accession
    NP_149024
    UniProt
    Q969D9
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