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IL7R Protein (AA 21-236) (Fc Tag)

IL7R Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6964160
  • Target See all IL7R Proteins
    IL7R (Interleukin 7 Receptor (IL7R))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-236
    Origin
    • 14
    • 5
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 10
    • 6
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL7R protein is labelled with Fc Tag.
    Purpose
    Recombinant Human IL7RA with C-terminal human Fc tag
    Specificity
    IL7RA (Glu21-Gly236) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product IL7R Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    IL7R (Interleukin 7 Receptor (IL7R))
    Alternative Name
    IL7RA (IL7R Products)
    Synonyms
    IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
    Background
    The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
    Molecular Weight
    predicted molecular mass of 51.0 kDa after removal of the signal peptide.The apparent molecular mass of IL7RA-hFc is 55-100 kDa due to glycosylation.
    UniProt
    P16871
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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