SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (Fc Tag)
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- Target See all SARS-CoV-2 Spike S1 Proteins
- SARS-CoV-2 Spike S1
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- P.1 - gamma
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Origin
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SARS-CoV-2 Spike S1 protein is labelled with Fc Tag.
- Purpose
- SARS-CoV-2 S1 protein (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y), Fc Tag
- Sequence
- AA 16-685
- Characteristics
- SARS-CoV-2 S1 protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). The mutations (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y) were identified in the SARS-CoV-2 variant (known as P.1) which emerged in Brazil.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- SARS-CoV-2 Spike S1
- Alternative Name
- SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 Products)
- Synonyms
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Target Type
- Viral Protein
- Background
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molecular Weight
- 101.5 kDa
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